HMGA2

Gene Symbol HMGA2
Entrez Gene 8091
Alt Symbol BABL, HMGI-C, HMGIC, LIPO, STQTL9
Species Human
Gene Type protein-coding
Description high mobility group AT-hook 2
Other Description High-mobility group protein HMGI-C|high mobility group protein HMGI-C|high-mobility group (nonhistone chromosomal) protein isoform I-C
Swissprots Q1M186 P52926 Q1M188 Q1M187 Q1M182 E7EP85 E7EWA2 Q1M185
Accessions AAA68614 AAA96484 AAN64002 CAA03408 CAB59170 EAW97152 P52926 AB209853 BAD93090 AF533651 AF533652 AF533653 AAO48741 AF533654 AAO48742 AI290477 AK311399 AK311443 AK311447 AY601861 AAU43851 AY601862 AAU43852 AY601863 AAU43853 AY601864 AAU43854 AY601865 AAU43855 AY601866 AAU43856 AY601867 AAU43857 BC160115 AAI60115 BM782659 CA422738 CN334368 U28749 AAA68613 U29112 U29113 U29115 U29119 X92518 CAA63295 Z31595 CAA83472 NM_001300918 NP_001287847 NM_001300919 NP_001287848 NM_003483 NP_003474 NM_003484 NP_003475 NM_001015886
Function Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. {ECO:0000269|PubMed:14645522}.
Subcellular Location Nucleus.
Top Pathways MicroRNAs in cancer, Transcriptional misregulation in cancer

HMGA2 (D1A7) Rabbit mAb - 8179 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1A7
Western blot analysis of extracts from various cell lines using HMGA2 (D1A7) Rabbit mAb.

HMGA2 Antibody - 5269 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using HMGA2 Antibody.

HMGI-C (FL-109) - sc-30223 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HMGI-C (FL-109): sc-30223. Immunofluorescence staining of methanol-fixed HeLa cells showing diffused nuclear localization.

HMGI-C (S-15) - sc-23684 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HMGI-C (S-15): sc-23684. Western blot analysis of human recombinant HMGI-C fusion protein.

HMGI-C (2421C6a) - sc-130024 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HMGI-C (2421C6a): sc-130024. Western blot analysis of human recombinant HMGI-C fusion protein.

Anti-HMGA2 antibody - ab52039 from Abcam

Prices $384.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Human breast carcinoma stained with Anti-HMGA2 antibody, ab52039 at 1:50 for 30 min at RT

Anti-HMGA2 antibody - ab97276 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HMGA2 antibody (ab97276) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

Anti-HMGA2 antibody - ab56390 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing HepG2 cells stained with ab56390 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab56390, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HepG2 cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-HMGA2 antibody [GT763] - ab184616 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GT763
Anti-HMGA2 antibody [GT763] (ab184616) at 1/1000 dilution + HepG2 whole cell lysate/extract at 30 µg

Anti-HMGA2 antibody, prediluted - ab52089 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Staining of HMGA2 in human breast carcinoma by immunohistochemistry (formalin fixed, paraffin embedded section) using ab52089 (prediluted).

HMGA2 Antibody - 25810002 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HMGA2 Antibody [25810002] - Samples: Lane 1, Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2, RT-4 Lane 3, U-251MG sp Lane 4, Human Plasma Lane 5, Liver Lane 6, Tonsil Target weight [kDa]: 16, 12, 11 (splice variants) Validation score: 2 Validation description: Supportive - Band of predicted size in kDa (+/-20%) with additional bands present.

HMGA2 Antibody [Unconjugated] - AF3184 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, MDA‑MD‑231 human breast cancer cell line, NIH‑3T3 mouse embryonic fibroblast cell line, and P19 mouse embryonal carcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse HMGA2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3184) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for HMGA2 at approximately 21 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

HMGA2 Antibody (1D8) - H00008091-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D8
Immunocytochemistry/Immunofluorescence: HMGA2 Antibody (1D8) [H00008091-M02] - Analysis of monoclonal antibody to HMGA2 on HeLa cell. Antibody concentration 10 ug/ml.

HMGA2 Antibody - NBP1-51985 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: HMGA2 Antibody [NBP1-51985] - (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HMGA2 Antibody - H00008091-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

HMGA2 Antibody (2D3) - H00008091-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D3
Immunocytochemistry/Immunofluorescence: HMGA2 Antibody (2D3) [H00008091-M04] - Analysis of monoclonal antibody to HMGA2 on HeLa cell. Antibody concentration 10 ug/ml

HMGA2 Polyclonal Antibody - bs-0556R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human ovary carcinoma labeled with Anti-HMGA2 Polyclonal Antibody (bs-0556R), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining

Rabbit Anti-HMGA2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0556R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HMGA2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0556R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HMGA2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0556R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HMGA2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0556R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HMGA2 Polyclonal Antibody, Cy3 Conjugated - bs-0556R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HMGA2 Polyclonal Antibody, Cy5 Conjugated - bs-0556R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HMGA2 Polyclonal Antibody, Cy5.5 Conjugated - bs-0556R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HMGA2 Polyclonal Antibody, Cy7 Conjugated - bs-0556R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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