Anti-NEDD4-2 antibody
| Name | Anti-NEDD4-2 antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab58093 |
| Prices | $384.00 |
| Sizes | 100 µg |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Applications | WB IP IHC-P |
| Species Reactivities | Human |
| Antigen | Recombinant fragment: MATGLGEPVY GLSEDEGESR ILRVKVVSGI DLAKKDIFGA SDPYVKLSLY VADENRELAL VQTKTIKKTL NPKWNEEFYF RVNPSNHRLL FEVFDENRLT , corresponding to amino acids 1-100 of Human NEDD4-2 Run BLAST with Run BLAST with |
| Description | Mouse Monoclonal |
| Gene | NEDD4L |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Western blot against tagged recombinant protein immunogen using ab58093 NEDD4-2 antibody at 1ug/ml.
IHC image of ab58093 staining in normal human colon formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab58093, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.
Product References
Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse - Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse
Das S, Aiba T, Rosenberg M, Hessler K, Xiao C, Quintero PA, Ottaviano FG, Knight AC, Graham EL, Bostrom P, Morissette MR, del Monte F, Begley MJ, Cantley LC, Ellinor PT, Tomaselli GF, Rosenzweig A. Circulation. 2012 Oct 30;126(18):2208-19.
Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 - Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1
Simonin A, Fuster D. J Biol Chem. 2010 Dec 3;285(49):38293-303.
Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway. - Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway.
Caohuy H, Jozwik C, Pollard HB. J Biol Chem. 2009 Sep 11;284(37):25241-53.