Anti-Niemann Pick C1 antibody
| Name | Anti-Niemann Pick C1 antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab36983 |
| Prices | $395.00 |
| Sizes | 100 µl |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | Electron microscopy WB ICC/IF ICC/IF IP |
| Species Reactivities | Mouse, Rat, Hamster, Human |
| Antigen | Synthetic peptide made to the C terminal region of human Niemann Pick C1 |
| Description | Rabbit Polyclonal |
| Gene | NPC1 |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
ab36983 at a 1/800 dilution staining Niemann Pick C1 in mouse 3T3-L1 cells by Immunocytochemistry/ Immunofluorescence, incubated for 12 hours at 4°C. Fixed in methanol. Blocked with 1% BSA for 1 hour 30 minutes at room temperature. Secondary used at 1/800 dilution monoclonal Goat anti-rabbit conjugated to Alexa Fluor 568 (red). Nucleus was stained with DAPI (blue).Note localization of Niemann Pick C1 around the nucleus and in cytosolic vesicles.See Abreview
Product References
Endoplasmic reticulum-associated degradation of Niemann-Pick C1: evidence for the - Endoplasmic reticulum-associated degradation of Niemann-Pick C1: evidence for the
Nakasone N, Nakamura YS, Higaki K, Oumi N, Ohno K, Ninomiya H. J Biol Chem. 2014 Jul 11;289(28):19714-25.
Ryanodine receptor antagonists adapt NPC1 proteostasis to ameliorate lipid - Ryanodine receptor antagonists adapt NPC1 proteostasis to ameliorate lipid
Yu T, Chung C, Shen D, Xu H, Lieberman AP. Hum Mol Genet. 2012 Jul 15;21(14):3205-14.
Disruption and therapeutic rescue of autophagy in a human neuronal model of - Disruption and therapeutic rescue of autophagy in a human neuronal model of
Ordonez MP, Roberts EA, Kidwell CU, Yuan SH, Plaisted WC, Goldstein LS. Hum Mol Genet. 2012 Jun 15;21(12):2651-62.
Altered vitamin E status in Niemann-Pick type C disease. - Altered vitamin E status in Niemann-Pick type C disease.
Ulatowski L, Parker R, Davidson C, Yanjanin N, Kelley TJ, Corey D, Atkinson J, Porter F, Arai H, Walkley SU, Manor D. J Lipid Res. 2011 Jul;52(7):1400-10.
Temporal and cell-specific deletion establishes that neuronal Npc1 deficiency is - Temporal and cell-specific deletion establishes that neuronal Npc1 deficiency is
Yu T, Shakkottai VG, Chung C, Lieberman AP. Hum Mol Genet. 2011 Nov 15;20(22):4440-51.
A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol - A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol
Du X, Kumar J, Ferguson C, Schulz TA, Ong YS, Hong W, Prinz WA, Parton RG, Brown AJ, Yang H. J Cell Biol. 2011 Jan 10;192(1):121-35.
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus - Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus
Cote M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. Nature. 2011 Aug 24;477(7364):344-8.
Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell - Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell
Elrick MJ, Pacheco CD, Yu T, Dadgar N, Shakkottai VG, Ware C, Paulson HL, Lieberman AP. Hum Mol Genet. 2010 Mar 1;19(5):837-47.
Recovery from liver disease in a Niemann-Pick type C mouse model. - Recovery from liver disease in a Niemann-Pick type C mouse model.
Sayre NL, Rimkunas VM, Graham MJ, Crooke RM, Liscum L. J Lipid Res. 2010 Aug;51(8):2372-83.
TNF-{alpha} plays a role in hepatocyte apoptosis in Niemann-Pick type C liver - TNF-{alpha} plays a role in hepatocyte apoptosis in Niemann-Pick type C liver
Rimkunas VM, Graham MJ, Crooke RM, Liscum L. J Lipid Res. 2009 Feb;50(2):327-33.