Anti-Noxa antibody [114C307]
| Name | Anti-Noxa antibody [114C307] |
|---|---|
| Supplier | Abcam |
| Catalog | ab13654 |
| Prices | $392.00 |
| Sizes | 100 µg |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone | 114C307 |
| Applications | FC WB |
| Species Reactivities | Mouse, Human |
| Antigen | Fusion protein containing human Noxa |
| Description | Mouse Monoclonal |
| Gene | PMAIP1 |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Western blot detection of Noxa in RL-7 cell (a follicular lymphoma) lysate. A protein of approximate molecular weight of 11 kDa is detected using ab13654 at 2 µg/ml.
 used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in Jurkat cells fixed with 80% methanol/permeabilized in 0.1% PBS-Tween used under the same conditions.](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_4/1576_Noxa-Primary-antibodies-ab13654-2.jpg)
Overlay histogram showing Jurkat cells stained with ab13654 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab13654, 1µg/1x106 cells) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1](ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in Jurkat cells fixed with 80% methanol/permeabilized in 0.1% PBS-Tween used under the same conditions.
Product References
Interferon-gamma-induced upregulation of immunoproteasome subunit assembly - Interferon-gamma-induced upregulation of immunoproteasome subunit assembly
Niewerth D, Kaspers GJ, Assaraf YG, van Meerloo J, Kirk CJ, Anderl J, Blank JL, van de Ven PM, Zweegman S, Jansen G, Cloos J. J Hematol Oncol. 2014 Jan 13;7:7.
Lineage of origin in rhabdomyosarcoma informs pharmacological response. - Lineage of origin in rhabdomyosarcoma informs pharmacological response.
Abraham J, Nunez-Alvarez Y, Hettmer S, Carrio E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C. Genes Dev. 2014 Jul 15;28(14):1578-91.
The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell - The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell
Geserick P, Wang J, Feoktistova M, Leverkus M. Cell Death Dis. 2014 Sep 11;5:e1412.
Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle - Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle
Sachweh MC, Drummond CJ, Higgins M, Campbell J, Lain S. Cell Death Dis. 2013 Mar 7;4:e533.
Small molecule induced reactivation of mutant p53 in cancer cells. - Small molecule induced reactivation of mutant p53 in cancer cells.
Liu X, Wilcken R, Joerger AC, Chuckowree IS, Amin J, Spencer J, Fersht AR. Nucleic Acids Res. 2013 Jul;41(12):6034-44.
Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by - Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by
Verfaillie T, van Vliet A, Garg AD, Dewaele M, Rubio N, Gupta S, de Witte P, Samali A, Agostinis P. Biochem Biophys Res Commun. 2013 Aug 30;438(3):500-6. doi:
Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP - Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP
Kerr E, Holohan C, McLaughlin KM, Majkut J, Dolan S, Redmond K, Riley J, McLaughlin K, Stasik I, Crudden M, Van Schaeybroeck S, Fenning C, O'Connor R, Kiely P, Sgobba M, Haigh D, Johnston PG, Longley DB. Cell Death Differ. 2012 Aug;19(8):1317-27.
Inhibitory role of E2F-1 in the regulation of tumor suppressor p53 during DNA - Inhibitory role of E2F-1 in the regulation of tumor suppressor p53 during DNA
Yoshihara Y, Wu D, Kubo N, Sang M, Nakagawara A, Ozaki T. Biochem Biophys Res Commun. 2012 Apr 27;421(1):57-63. doi:
Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and - Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and
Sun R, Zhang Y, Lv Q, Liu B, Jin M, Zhang W, He Q, Deng M, Liu X, Li G, Li Y, Zhou G, Xie P, Xie X, Hu J, Duan Z. J Biol Chem. 2011 May 6;286(18):15918-28.
Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 - Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2
Morales AA, Kurtoglu M, Matulis SM, Liu J, Siefker D, Gutman DM, Kaufman JL, Lee KP, Lonial S, Boise LH. Blood. 2011 Aug 4;118(5):1329-39.