NALP5 Antibody

Name NALP5 Antibody
Supplier ABBIOTEC
Catalog 254345
Prices $292.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Applications ELISA WB
Species Reactivities Human
Antigen KLH-conjugated synthetic peptide encompassing a sequence within human NALP5.
Purity/Format Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Description NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
Gene NLRP5
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