Gene Symbol | NLRP5 |
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Entrez Gene | 126206 |
Alt Symbol | CLR19.8, MATER, NALP5, PAN11, PYPAF8 |
Species | Human |
Gene Type | protein-coding |
Description | NLR family, pyrin domain containing 5 |
Other Description | NACHT, LRR and PYD domains-containing protein 5|NACHT, leucine rich repeat and PYD containing 5|mater protein homolog|maternal antigen that embryos require|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 |
Swissprots | Q86W29 P59047 A8MTY4 |
Accessions | P59047 AY054986 AAL15549 AY154460 AAO18156 BC141431 AAI41432 XM_011526444 XP_011524746 NM_153447 NP_703148 |
Function | As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity). {ECO:0000250}. |
Tissue Specificity | Oocyte-specific. |
NALP5 (T-20) - sc-50630 from Santa Cruz Biotechnology
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Anti-NALP5 antibody - ab105324 from Abcam
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Anti-NALP5 antibody - ab185679 from Abcam
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Anti-NLRP5 / NALP5 Antibody (aa215-232) - LS-C148967 from LifeSpan Bioscience
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Anti-NLRP5 / NALP5 Antibody (aa121-170) - LS-C135481 from LifeSpan Bioscience
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Anti-NLRP5 / NALP5 Antibody (C-Terminus) - LS-C115897 from LifeSpan Bioscience
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NLRP5 Antibody - NBP1-76289 from Novus Biologicals
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NLRP5 Antibody - 45740002 from Novus Biologicals
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NLRP5 Antibody - NBP1-69159 from Novus Biologicals
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Anti-NALP5 antibody produced in rabbit - SAB3500549 from Sigma-Aldrich
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Anti-NLRP5 antibody produced in rabbit - SAB2107359 from Sigma-Aldrich
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Anti-NLRP5 (221-235) antibody produced in rabbit - SAB1104161 from Sigma-Aldrich
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Anti-NLRP5 antibody produced in rabbit - HPA056271 from Sigma-Aldrich
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NLRP5 antibody - N-terminal region (ARP59021_P050) - ARP59021_P050 from Aviva Systems Biology
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NALP5 antibody - GTX85158 from GeneTex
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NALP5 antibody - orb75486 from Biorbyt
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NLRP5 antibody - 70R-9657 from Fitzgerald
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NLRP5 (C-term) antibody - AP26262PU-N from Acris Antibodies
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NLRP5 antibody - H00126206-B01P from Acris Antibodies
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NALP5 Antibody - 5959 from ProSci
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NALP5 Antibody - 254345 from ABBIOTEC
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NALP5 Antibody - 25180 from Signalway Antibody
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NLRP5 Antibody - GWB-MV470B from Genway Biotech
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Anti-NLRP5 (aa 399-513) polyclonal antibody - DPABH-14968 from Creative Diagnostics
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Anti-NLRP5 (C-terminal) polyclonal antibody - DPAB-L20793 from Creative Diagnostics
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