Anti-SOCS3 antibody
| Name | Anti-SOCS3 antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab3693 |
| Prices | $391.00 |
| Sizes | 50 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC-P WB IP |
| Species Reactivities | Mouse, Human, Rat |
| Antigen | Synthetic peptide ( QLPGPIREFLDQYDAPL ), corresponding to amino acids 209-225 of the human/ rat/ mouse SOCS 3 |
| Description | Rabbit Polyclonal |
| Gene | SOCS3 |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Localization of ab3693 as the precipitated red signal, with a hematoxylin purple nuclear counterstain in cardiac myocytes.
ab3693 (2µg/ml) staining SOCS3 in human jejunum using an automated system (DAKO Autostainer Plus). Using this protocol there is staining of the cells within the lamina propria.Sections were rehydrated and antigen retrieved with the Dako 3 in 1 AR buffers EDTA pH 9.0 in a DAKO PT link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 mins. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 min and detected with Dako envision flex amplification kit for 30 minutes. Colorimetric detection was completed with Diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that, for manual staining, optimization of primary antibody concentration and incubation time is recommended. Signal amplification may be required.
Product References
Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation - Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation
Akram KM, Lomas NJ, Forsyth NR, Spiteri MA. Int J Clin Exp Pathol. 2014 Jan 15;7(2):552-64. eCollection 2014.
STAT3 activation in skeletal muscle links muscle wasting and the acute phase - STAT3 activation in skeletal muscle links muscle wasting and the acute phase
Bonetto A, Aydogdu T, Kunzevitzky N, Guttridge DC, Khuri S, Koniaris LG, Zimmers TA. PLoS One. 2011;6(7):e22538.
Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin - Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin
Kleemann R, van Erk M, Verschuren L, van den Hoek AM, Koek M, Wielinga PY, Jie A, Pellis L, Bobeldijk-Pastorova I, Kelder T, Toet K, Wopereis S, Cnubben N, Evelo C, van Ommen B, Kooistra T. PLoS One. 2010 Jan 21;5(1):e8817.
Signaling pathways involved in liver injury and regeneration in rabbit - Signaling pathways involved in liver injury and regeneration in rabbit
Garcia-Lastra R, San-Miguel B, Crespo I, Jorquera F, Alvarez M, Gonzalez-Gallego J, Tunon MJ. Vet Res. 2010 Jan-Feb;41(1):2.
Modulation of SOCS protein expression influences the interferon responsiveness of - Modulation of SOCS protein expression influences the interferon responsiveness of
Lesinski GB, Zimmerer JM, Kreiner M, Trefry J, Bill MA, Young GS, Becknell B, Carson WE 3rd. BMC Cancer. 2010 Apr 14;10:142.
Extended anti-inflammatory action of a degradation-resistant mutant of - Extended anti-inflammatory action of a degradation-resistant mutant of
Fletcher TC, DiGiandomenico A, Hawiger J. J Biol Chem. 2010 Jun 11;285(24):18727-36.
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links - An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links
Iliopoulos D, Hirsch HA, Struhl K. Cell. 2009 Nov 13;139(4):693-706.
Erythropoietin promotes axonal growth in a model of neuronal polarization. - Erythropoietin promotes axonal growth in a model of neuronal polarization.
Ransome MI, Turnley AM. Mol Cell Neurosci. 2008 Aug;38(4):537-47.
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and - SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and
Orabona C, Pallotta MT, Volpi C, Fallarino F, Vacca C, Bianchi R, Belladonna ML, Fioretti MC, Grohmann U, Puccetti P. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20828-33. doi:
Defective hepatic response to interferon and activation of suppressor of cytokine - Defective hepatic response to interferon and activation of suppressor of cytokine
Huang Y, Feld JJ, Sapp RK, Nanda S, Lin JH, Blatt LM, Fried MW, Murthy K, Liang TJ. Gastroenterology. 2007 Feb;132(2):733-44. Epub 2006 Nov 29.