Anti-Urokinase antibody

• Supplier: Abcam
• Catalog: ab24121
• Prices: $394.00
• Sizes: 100 µg
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Applications: ICC/IF ICC/IF WB DB IHC-F IHC-P ELISA RIA
• Species Reactivities: Human
• Antigen: Full length protein (Human)
• Description: Rabbit Polyclonal
• Gene: PLAU
• Conjugate: Unconjugated

Product images

ICC/IF image of ab24121 stained DU145 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab24121 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

ab24121 at 1/200 dilution staining HMW-scuPA in human brain tissue by immunohistochemistry (formalin/PFA-fixed paraffin-embedded sections). Sections were formaldehyde fixed prior to blocking in 10% serum for 12 hours at room temperature and then incubated with ab24121, for 18 hours at 4°C. A goat monoclonal to rabbit Ig, diluted 1/50, was used as the secondary antibody.See Abreview

Product References

uPA binding to PAI-1 induces corneal myofibroblast differentiation on - uPA binding to PAI-1 induces corneal myofibroblast differentiation on

Wang L, Ly CM, Ko CY, Meyers EE, Lawrence DA, Bernstein AM. Invest Ophthalmol Vis Sci. 2012 Jul 13;53(8):4765-75.

Regulation of extravillous trophoblast invasion by uterine natural killer cells - Regulation of extravillous trophoblast invasion by uterine natural killer cells

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Plasmin in nephrotic urine activates the epithelial sodium channel. - Plasmin in nephrotic urine activates the epithelial sodium channel.

Svenningsen P, Bistrup C, Friis UG, Bertog M, Haerteis S, Krueger B, Stubbe J, Jensen ON, Thiesson HC, Uhrenholt TR, Jespersen B, Jensen BL, Korbmacher C, Skott O. J Am Soc Nephrol. 2009 Feb;20(2):299-310.

Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance - Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance

Chen H, Hao J, Wang L, Li Y. Br J Cancer. 2009 Aug 4;101(3):432-40.

FAP-alpha and uPA show different expression patterns in premalignant and - FAP-alpha and uPA show different expression patterns in premalignant and

Goscinski MA, Suo Z, Florenes VA, Vlatkovic L, Nesland JM, Giercksky KE. Ultrastruct Pathol. 2008 May-Jun;32(3):89-96.