Anti-EGLN1 / PHD2 Antibody (aa1-50) IHC-plusâ¢
| Name | Anti-EGLN1 / PHD2 Antibody (aa1-50) IHC-plus⢠|
|---|---|
| Supplier | LifeSpan Bioscience |
| Catalog | LS-B4810 |
| Prices | $395.00 |
| Sizes | 100 µl |
| Host | Rabbit |
| Clonality | Polyclonal |
| Applications | ELISA |
| Species Reactivities | Human |
| Antigen | EGLN1 / PHD2 antibody was raised against the epitope recognized by this antibody maps to a region between residues 1 and 50 of human Prolyl Hydroxylase Domain-Containing Protein 2 using the numbering given in entry NP_071334.1 (GeneID 54583) |
| Purity/Format | Immunoaffinity purified |
| Description | Rabbit Polyclonal |
| Gene | EGLN1 |
| Conjugate | Unconjugated. Also available conjugated with Biotin , DY650 , DY488 , DY550 . |
| Supplier Page | Shop |
Product images
Anti-EGLN1 / PHD2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4810 concentration 5 ug/ml.
Anti-EGLN1 / PHD2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4810 concentration 5 ug/ml.
Western blot of human PHD2. Samples: Recombinant FLAG-His-PHD1, PHD2 or PHD3 (10 ng/lane) and whole cell lysate from HeLa cells.
Product References
Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase - Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase
Asikainen TM, Schneider BK, Waleh NS, Clyman RI, Ho WB, Flippin LA, Gunzler V, White CW. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10212-7. Epub 2005 Jul 11.
The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible - The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible
Barth S, Nesper J, Hasgall PA, Wirthner R, Nytko KJ, Edlich F, Katschinski DM, Stiehl DP, Wenger RH, Camenisch G. Mol Cell Biol. 2007 May;27(10):3758-68. Epub 2007 Mar 12.
Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation. - Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation.
Rantanen K, Pursiheimo J, Hogel H, Himanen V, Metzen E, Jaakkola PM. Mol Biol Cell. 2008 May;19(5):2231-40.
Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 - Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2
Aprelikova O, Pandolfi S, Tackett S, Ferreira M, Salnikow K, Ward Y, Risinger JI, Barrett JC, Niederhuber J. Cancer Res. 2009 Jan 15;69(2):616-24.
Prolyl hydroxylase 2 deficiency limits proliferation of vascular smooth muscle - Prolyl hydroxylase 2 deficiency limits proliferation of vascular smooth muscle
Schultz K, Murthy V, Tatro JB, Beasley D. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L921-7. doi:
Prolyl hydroxylase domain (PHD) 2 affects cell migration and F-actin formation - Prolyl hydroxylase domain (PHD) 2 affects cell migration and F-actin formation
Vogel S, Wottawa M, Farhat K, Zieseniss A, Schnelle M, Le-Huu S, von Ahlen M, Malz C, Camenisch G, Katschinski DM. J Biol Chem. 2010 Oct 29;285(44):33756-63.
Hypoxia-inducible factor-1alpha contributes to the profibrotic action of - Hypoxia-inducible factor-1alpha contributes to the profibrotic action of
Wang Z, Tang L, Zhu Q, Yi F, Zhang F, Li PL, Li N. Kidney Int. 2011 Feb;79(3):300-10.
The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic - The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic
Brockmeier U, Platzek C, Schneider K, Patak P, Bernardini A, Fandrey J, Metzen E. PLoS One. 2011 Apr 29;6(4):e19151.
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor - Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor
Luo W, Hu H, Chang R, Zhong J, Knabel M, O'Meally R, Cole RN, Pandey A, Semenza GL. Cell. 2011 May 27;145(5):732-44.
Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2. - Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2.
Nandal A, Ruiz JC, Subramanian P, Ghimire-Rijal S, Sinnamon RA, Stemmler TL, Bruick RK, Philpott CC. Cell Metab. 2011 Nov 2;14(5):647-57.