Anti-RRM2B / P53R2 Antibody (N-Terminus)
| Name | Anti-RRM2B / P53R2 Antibody (N-Terminus) |
|---|---|
| Supplier | LifeSpan Bioscience |
| Catalog | LS-C154254 |
| Prices | $395.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC-P WB |
| Species Reactivities | Human |
| Antigen | RRM2B / P53R2 antibody was raised against anti-Human RRM2B/p53R2 antibody was prepared by repeated immunizations with a synthetic peptide corresponding to a region near the N-terminus of human RRM2B1 protein. A residue of cysteine was added to facilitate coupling. |
| Purity/Format | Purified |
| Description | Rabbit Polyclonal |
| Gene | RRM2B |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Anti-RRM2B antibody - Western Blot. Western blot of affinity purified anti-RRM2B antibody shows detection of recombinant (lanes 1 and 3) and endogenous protein (lanes 1 to 4) in whole cell extracts from transfected 293T. Lane 1 contains purified recombinant human p53R2. Lane 2 contains 293T cells transfected with control vector. Lane 3 contains 293T transfected with p53R2-myc. Lane 4:293T transfected with ScRNA. Lane 5:293T transfected with p53R2 SiRNA The band at 40.7 kD, indicated by the bottom arrowhead, corresponds to the expected molecular weight of endogenous RRM2B. The band with the middle arrow corresponds to myc-tagged p53R2 at 41.9kD. The highest band at 44.3 kD corresponds to recombinant p53R2. Primary antibody was diluted to 1 ug/mL and incubated overnight at 4C. ECL detection was used.
Product References
Ribonucleotide reductase small subunit M2B prognoses better survival in - Ribonucleotide reductase small subunit M2B prognoses better survival in
Liu X, Lai L, Wang X, Xue L, Leora S, Wu J, Hu S, Zhang K, Kuo ML, Zhou L, Zhang H, Wang Y, Wang Y, Zhou B, Nelson RA, Zheng S, Zhang S, Chu P, Yen Y. Cancer Res. 2011 May 1;71(9):3202-13.
Ribonucleotide reductase subunit p53R2 regulates mitochondria homeostasis and - Ribonucleotide reductase subunit p53R2 regulates mitochondria homeostasis and
Wang X, Liu X, Xue L, Zhang K, Kuo ML, Hu S, Zhou B, Ann D, Zhang S, Yen Y. Biochem Biophys Res Commun. 2011 Jun 24;410(1):102-7. doi:
RRM2B suppresses activation of the oxidative stress pathway and is up-regulated - RRM2B suppresses activation of the oxidative stress pathway and is up-regulated
Kuo ML, Sy AJ, Xue L, Chi M, Lee MT, Yen T, Chiang MI, Chang L, Chu P, Yen Y. Sci Rep. 2012;2:822.