Anti-FRAT1 (C-terminal region) antibody produced in rabbit

• Supplier: Sigma-Aldrich
• Catalog: F9181
• Prices: $57.50, $315.50
• Sizes: 25 µl, 200 µl
• Host: Rabbit
• Clonality: Polyclonal
• Applications: WB
• Species Reactivities: Human
• Antigen: synthetic peptide corresponding to amino acids 238-252 of human FRAT1, conjugated to KLH
• Description: Rabbit Polyclonal
• Gene: FRAT1
• Conjugate: unconjugated

Product images

Immunoblotting
Cell lysates of HEK-293T overexpressing human FRAT1 (lanes 1,2) and of HEK-293T non-transfected (Lane 3), were separated on SDS-PAGE, blotted with Anti-FRAT1 (C-terminal region) (Cat. No. F9181) and developed using Goat Anti-Rabbit IgG-Peroxidase (Cat. No. A0545) and chemiluminescent substrate.
Lanes
1. Antibody: 1.5 μg/mL
2. Antibody: 1.5 μg/mL + FRAT1 immunizing peptide (human, 238-252)
3. Antibody: 1.5 μg/mL

Product References

Overexpression of Frat1 correlates with malignant phenotype and advanced stage in - Overexpression of Frat1 correlates with malignant phenotype and advanced stage in

Zhang Y, Yu JH, Lin XY, Miao Y, Han Y, Fan CF, Dong XJ, Dai SD, Wang EH. Virchows Arch. 2011 Sep;459(3):255-63.

FRAT1 overexpression leads to aberrant activation of beta-catenin/TCF pathway in - FRAT1 overexpression leads to aberrant activation of beta-catenin/TCF pathway in

Wang Y, Liu S, Zhu H, Zhang W, Zhang G, Zhou X, Zhou C, Quan L, Bai J, Xue L, Lu N, Xu N. Int J Cancer. 2008 Aug 1;123(3):561-8.

Characterization and functional analysis of the murine Frat2 gene. - Characterization and functional analysis of the murine Frat2 gene.

van Amerongen R, van der Gulden H, Bleeker F, Jonkers J, Berns A. J Biol Chem. 2004 Jun 25;279(26):26967-74. Epub 2004 Apr 8.

Characterization and tissue-specific expression of human GSK-3-binding proteins - Characterization and tissue-specific expression of human GSK-3-binding proteins

Freemantle SJ, Portland HB, Ewings K, Dmitrovsky F, DiPetrillo K, Spinella MJ, Dmitrovsky E. Gene. 2002 May 29;291(1-2):17-27.

Molecular cloning and expression of proto-oncogene FRAT1 in human cancer. - Molecular cloning and expression of proto-oncogene FRAT1 in human cancer.

Saitoh T, Mine T, Katoh M. Int J Oncol. 2002 Apr;20(4):785-9.

Molecular cloning and characterization of FRAT2, encoding a positive regulator of - Molecular cloning and characterization of FRAT2, encoding a positive regulator of

Saitoh T, Moriwaki J, Koike J, Takagi A, Miwa T, Shiokawa K, Katoh M. Biochem Biophys Res Commun. 2001 Mar 2;281(3):815-20.

WNT targets. Repression and activation. - WNT targets. Repression and activation.

Nusse R. Trends Genet. 1999 Jan;15(1):1-3.

WNT signaling in stem cell biology and regenerative medicine. - WNT signaling in stem cell biology and regenerative medicine.

Katoh M. Curr Drug Targets. 2008 Jul;9(7):565-70.