FRAT1

Gene Symbol	FRAT1
Entrez Gene	10023
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	frequently rearranged in advanced T-cell lymphomas 1
Other Description	FRAT-1\|proto-oncogene FRAT1
Swissprots	Q5JTI1 Q8NE74 Q8TDW9 Q92837
Accessions	EAW49950 EAW49951 Q92837 AB074890 BAB86352 AK307245 BC034476 AAH34476 BE041458 U58975 AAB97096 NM_005479 NP_005470 NM_181355
Function	Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. {ECO:0000269\|PubMed:12556519}.
Subcellular Location	Cytoplasm.
Top Pathways	Wnt signaling pathway

FRAT1 (C-17) - sc-8444 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FRAT1 (N-20) - sc-8443 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FRAT1 (N-20): sc-8443. Western blot analysis of FRAT1 expression in rat liver tissue extract.

FRAT1 (S-20) - sc-8445 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FRAT1 (S-20): sc-8445. Western blot analysis of FRAT1 expression in HeLa whole cell lysate.

FRAT1 (U-25) - sc-130756 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

FRAT1 (U-25): sc-130756. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic localization.

Anti-FRAT1 antibody [EPR3900] - ab108405 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR3900

All lanes : Anti-FRAT1 antibody [EPR3900] (ab108405) at 1/1000 dilutionLane 1 : HeLa cell lysate Lane 2 : MCF7 cell lysate Lysates/proteins at 10 µg per lane.

Anti-FRAT1 antibody - C-terminal - ab137391 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRAT1 antibody - C-terminal (ab137391) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-FRAT1 antibody - C-terminal - ab70918 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-FRAT1 antibody - C-terminal (ab70918) at 1/50 dilutionLane 1 : Nontransfected 293 cell line lysatesLane 2 : 293 cell line lysates transiently transfected with the FRAT1 geneLysates/proteins at 2 µg per lane.

Anti-FRAT1 Antibody (Internal, clone EPR3900) - LS-C138010 from LifeSpan Bioscience

Prices	$450.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR3900

Western blot analysis on (A) HeLa and (B) MCF-7 cell lysates using anti-FRAT1 antibody.

Anti-FRAT1 Antibody (aa99-128) - LS-C98154 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FRAT1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-FRAT1 Antibody (aa244-274) - LS-C98153 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Antibody - NBP1-31213 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: FRAT1 Antibody [NBP1-31213] - Sample(30 ug whole cell lysate) A:A431 12% SDS PAGE diluted at 1:1000

FRAT1 Polyclonal Antibody - bs-12434R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12434R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12434R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12434R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12434R-A647 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, Cy3 Conjugated - bs-12434R-Cy3 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, Cy5 Conjugated - bs-12434R-Cy5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, Cy5.5 Conjugated - bs-12434R-Cy5.5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, Cy7 Conjugated - bs-12434R-Cy7 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, FITC Conjugated - bs-12434R-FITC from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, Biotin Conjugated - bs-12434R-Biotin from Bioss

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

FRAT1 Polyclonal Antibody, HRP Conjugated - bs-12434R-HRP from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRAT1 (C-terminal region) antibody produced in rabbit - F9181 from Sigma-Aldrich

Prices	$57.50, $315.50
Sizes	25 µl, 200 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell lysates of HEK-293T overexpressing human FRAT1 (lanes 1,2) and of HEK-293T non-transfected (Lane 3), were separated on SDS-PAGE, blotted with Anti-FRAT1 (C-terminal region) (<B>Cat. No. F9181</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody: 1.5 μg/mL<BR/>2. Antibody: 1.5 μg/mL + FRAT1 immunizing peptide (human, 238-252)<BR/>3. Antibody: 1.5 μg/mL

Anti-FRAT1 (center) antibody produced in rabbit - SAB1300542 from Sigma-Aldrich

Prices	$291.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-FRAT1 (Center) Antibody: <B>Cat. No. SAB1300542</B>: FRat1 in HEK 293 cell line lysates either non-transfected (Lane 1) or transiently transfected (Lane 2) with Anti-FRat1 (Center) Antibody at 4.0 μg/mL.

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