Monoclonal Anti-E2F6 antibody produced in mouse

• Supplier: Sigma-Aldrich
• Catalog: E1532
• Prices: $63.50, $413.50
• Sizes: 25 µl, 200 µl
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone: TFE61
• Applications: ICC/IF ELISA WB
• Species Reactivities: Human
• Antigen: recombinant human E2F6 protein
• Description: Mouse Monoclonal
• Gene: E2F6
• Conjugate: unconjugated

Product images

Immunoblotting
Nuclear extract of HeLa cells was separated on SDS-PAGE and incubated with serial concentrations of Monoclonal Anti-E2F6 (Cat. No. E1532). The antibody was developed with Goat Anti-Mouse IgG, Peroxidase conjugate (Cat. No. A2304) and a chemiluminescent substrate.
Lanes
1. 0.25 μg/mL antibody
2. 0.5 μg/mL antibody
3. 1 μg/mL antibody
4. 2 μg/mL antibody
5. 4 μg/mL antibody
6. 8 μg/mL antibody
7. negative control

Product References

E2F-6, a member of the E2F family that can behave as a transcriptional repressor. - E2F-6, a member of the E2F family that can behave as a transcriptional repressor.

Trimarchi JM, Fairchild B, Verona R, Moberg K, Andon N, Lees JA. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2850-5.

Unusual proliferation arrest and transcriptional control properties of a newly - Unusual proliferation arrest and transcriptional control properties of a newly

Gaubatz S, Wood JG, Livingston DM. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9190-5.

The E2F6 transcription factor is a component of the mammalian Bmi1-containing - The E2F6 transcription factor is a component of the mammalian Bmi1-containing

Trimarchi JM, Fairchild B, Wen J, Lees JA. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1519-24. Epub 2001 Jan 30.

E2F6 negatively regulates BRCA1 in human cancer cells without methylation of - E2F6 negatively regulates BRCA1 in human cancer cells without methylation of

Oberley MJ, Inman DR, Farnham PJ. J Biol Chem. 2003 Oct 24;278(43):42466-76. Epub 2003 Aug 8.

A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. - A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription.

Giangrande PH, Zhu W, Schlisio S, Sun X, Mori S, Gaubatz S, Nevins JR. Genes Dev. 2004 Dec 1;18(23):2941-51.

Characterization of a negative transcriptional element in the BRCA1 promoter. - Characterization of a negative transcriptional element in the BRCA1 promoter.

MacDonald G, Stramwasser M, Mueller CR. Breast Cancer Res. 2007;9(4):R49.

Life and death decisions by the E2F transcription factors. - Life and death decisions by the E2F transcription factors.

Iaquinta PJ, Lees JA. Curr Opin Cell Biol. 2007 Dec;19(6):649-57. Epub 2007 Nov 26.