Anti-UPF3B antibody produced in rabbit

Name	Anti-UPF3B antibody produced in rabbit
Supplier	Sigma-Aldrich
Catalog	HPA001800
Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal
Applications	IHC-P ICC/IF WB
Species Reactivities	Mouse, Human, Rat
Antigen	Regulator of nonsense transcripts 3B recombinant protein epitope signature tag (PrEST)
Description	Rabbit Polyclonal
Gene	UPF3B
Conjugate	unconjugated
Supplier Page	Shop

Product images

<B>Immunohistochemistry</B><BR/>Anti-UPF3B: <B>Cat. No. HPA001800</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human placenta tissue showing strong cytoplasmic and/or membranous staining of trophoblastic cells.

Immunohistochemistry
Anti-UPF3B: Cat. No. HPA001800: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human placenta tissue showing strong cytoplasmic and/or membranous staining of trophoblastic cells.

<B>Immunofluorescence</B><BR/>Anti-UPF3B: <B>Cat. No. HPA001800</B>: Immunofluorescent staining of human cell line A-431 shows positivity in nuclei & cytoplasm.

Immunofluorescence
Anti-UPF3B: Cat. No. HPA001800: Immunofluorescent staining of human cell line A-431 shows positivity in nuclei & cytoplasm.

<B>Immunoblotting</B><BR/>Anti-UPF3B: <B>Cat. No. HPA001800</B>:<BR/><B>Lanes</B><BR/>1. Marker [kDa] 219, 112, 85, 49, 32, 25, 18<BR/>2. Human cell line RT-4<BR/>3. Human cell line U-251MG sp<BR/>4. Human cell line A-431

Immunoblotting
Anti-UPF3B: Cat. No. HPA001800:
Lanes
1. Marker [kDa] 219, 112, 85, 49, 32, 25, 18
2. Human cell line RT-4
3. Human cell line U-251MG sp
4. Human cell line A-431

<B>Immunoblotting</B><BR/>Anti-UPF3B: <B>Cat. No. HPA001800</B>:<BR/><B>Lanes</B><BR/>1. NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)<BR/>2. NBT-II cell lysate (Rat Wistar bladder tumour cells)<BR/>3. PC12 cell lysate (Pheochromocytoma of rat adrenal medulla)

Immunoblotting
Anti-UPF3B: Cat. No. HPA001800:
Lanes
1. NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
2. NBT-II cell lysate (Rat Wistar bladder tumour cells)
3. PC12 cell lysate (Pheochromocytoma of rat adrenal medulla)

Product References

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate - NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate

Chamieh H, Ballut L, Bonneau F, Le Hir H. Nat Struct Mol Biol. 2008 Jan;15(1):85-93. Epub 2007 Dec 9.

Nonsense mediated decay induced by tethered human UPF3B is restricted to the - Nonsense mediated decay induced by tethered human UPF3B is restricted to the

Lu S, Cullen BR. RNA Biol. 2004 May;1(1):42-7. Epub 2004 May 8.

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. - Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation.

Kunz JB, Neu-Yilik G, Hentze MW, Kulozik AE, Gehring NH. RNA. 2006 Jun;12(6):1015-22. Epub 2006 Apr 6.

Exon-junction complex components specify distinct routes of nonsense-mediated - Exon-junction complex components specify distinct routes of nonsense-mediated

Gehring NH, Kunz JB, Neu-Yilik G, Breit S, Viegas MH, Hentze MW, Kulozik AE. Mol Cell. 2005 Oct 7;20(1):65-75.

Y14 and hUpf3b form an NMD-activating complex. - Y14 and hUpf3b form an NMD-activating complex.

Gehring NH, Neu-Yilik G, Schell T, Hentze MW, Kulozik AE. Mol Cell. 2003 Apr;11(4):939-49.

Human Upf proteins target an mRNA for nonsense-mediated decay when bound - Human Upf proteins target an mRNA for nonsense-mediated decay when bound

Lykke-Andersen J, Shu MD, Steitz JA. Cell. 2000 Dec 22;103(7):1121-31.