Anti-SIX1 antibody produced in rabbit
| Name | Anti-SIX1 antibody produced in rabbit |
|---|---|
| Supplier | Sigma-Aldrich |
| Catalog | HPA001893 |
| Prices | $429.00 |
| Sizes | 100 µl |
| Host | Rabbit |
| Clonality | Polyclonal |
| Applications | IHC-P ICC/IF WB |
| Species Reactivities | Mouse, Human |
| Antigen | Homeobox protein SIX1 recombinant protein epitope signature tag (PrEST) |
| Description | Rabbit Polyclonal |
| Gene | SIX1 |
| Conjugate | unconjugated |
| Supplier Page | Shop |
Product images
ImmunohistochemistryAnti-SIX1: Cat. No. HPA001893: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human skeletal muscle tissue showing positive nuclear staining of myocytes.
ImmunofluorescenceAnti-SIX1: Cat. No. HPA001893: Immunofluorescent staining of human cell line A-431 shows positivity in nuclei, cytoplasm & nucleoli.
![<B>Immunoblotting</B><BR/>Anti-SIX1: <B>Cat. No. HPA001893</B>:<BR/><B>Lanes</B><BR/>1. Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<BR/>2. Negative control (vector only transfected HEK293T lysate)<BR/>3. Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401814)](http://www.bioprodhub.com/system/product_images/ab_products/7/sub_3/8471_hpa001893-blot-1-l-large.jpg)
ImmunoblottingAnti-SIX1: Cat. No. HPA001893:
Lanes
1. Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
2. Negative control (vector only transfected HEK293T lysate)
3. Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401814)
ImmunoblottingAnti-SIX1: Cat. No. HPA001893:
Lanes
1. NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
2. NBT-II cell lysate (Rat Wistar bladder tumour cells)
Product References
SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA - SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA
Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM Jr, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F. Proc Natl Acad Sci U S A. 2004 May 25;101(21):8090-5. Epub 2004 May 12.
Upregulation of notch2 and six1 is associated with progression of early-stage - Upregulation of notch2 and six1 is associated with progression of early-stage
Mimae T, Okada M, Hagiyama M, Miyata Y, Tsutani Y, Inoue T, Murakami Y, Ito A. Clin Cancer Res. 2012 Feb 15;18(4):945-55.
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces - Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces
McCoy EL, Iwanaga R, Jedlicka P, Abbey NS, Chodosh LA, Heichman KA, Welm AL, Ford HL. J Clin Invest. 2009 Sep;119(9):2663-77.
The Six1 homeoprotein induces human mammary carcinoma cells to undergo - The Six1 homeoprotein induces human mammary carcinoma cells to undergo
Micalizzi DS, Christensen KL, Jedlicka P, Coletta RD, Baron AE, Harrell JC, Horwitz KB, Billheimer D, Heichman KA, Welm AL, Schiemann WP, Ford HL. J Clin Invest. 2009 Sep;119(9):2678-90.
Eya2 is required to mediate the pro-metastatic functions of Six1 via the - Eya2 is required to mediate the pro-metastatic functions of Six1 via the
Farabaugh SM, Micalizzi DS, Jedlicka P, Zhao R, Ford HL. Oncogene. 2012 Feb 2;31(5):552-62.
Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes - Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes
Iwanaga R, Wang CA, Micalizzi DS, Harrell JC, Jedlicka P, Sartorius CA, Kabos P, Farabaugh SM, Bradford AP, Ford HL. Breast Cancer Res. 2012 Jul 5;14(4):R100.
Six1 regulates stem cell repair potential and self-renewal during skeletal muscle - Six1 regulates stem cell repair potential and self-renewal during skeletal muscle
Le Grand F, Grifone R, Mourikis P, Houbron C, Gigaud C, Pujol J, Maillet M, Pages G, Rudnicki M, Tajbakhsh S, Maire P. J Cell Biol. 2012 Sep 3;198(5):815-32.
SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1 - SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1
Ono H, Imoto I, Kozaki K, Tsuda H, Matsui T, Kurasawa Y, Muramatsu T, Sugihara K, Inazawa J. Oncogene. 2012 Nov 22;31(47):4923-34.
The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces - The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces
Smith AL, Iwanaga R, Drasin DJ, Micalizzi DS, Vartuli RL, Tan AC, Ford HL. Oncogene. 2012 Dec 13;31(50):5162-71.
Gene expression changes during HPV-mediated carcinogenesis: a comparison between - Gene expression changes during HPV-mediated carcinogenesis: a comparison between
Wan F, Miao X, Quraishi I, Kennedy V, Creek KE, Pirisi L. Int J Cancer. 2008 Jul 1;123(1):32-40.