Anti-METTL3 antibody produced in rabbit

• Supplier: Sigma-Aldrich
• Catalog: HPA001299
• Prices: $429.00
• Sizes: 100 µl
• Host: Rabbit
• Clonality: Polyclonal
• Applications: IHC-P WB
• Species Reactivities: Human
• Antigen: Adenosine-N6 methyltransferase 70 kDa subunit recombinant protein epitope signature tag (PrEST)
• Description: Rabbit Polyclonal
• Gene: METTL3
• Conjugate: unconjugated

Product images

Immunohistochemistry
Anti-METTL3: Cat. No. HPA001299: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human appendix tissue showing cytoplasmic and/or membranous staining in lymphoid tissue.

Immunoblotting
Anti-METTL3: Cat. No. HPA001299:
Lanes
1. Marker [kDa] 219, 112, 85, 49, 32, 25, 18
2. Human cell line RT-4
3. Human cell line U-251MG sp
4. Human cell line A-431
5. Human liver tissue
6. Human tonsil tissue

Product References

Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA - Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA

Bokar JA, Shambaugh ME, Polayes D, Matera AG, Rottman FM. RNA. 1997 Nov;3(11):1233-47.

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. - Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.

Dominissini D, Moshitch-Moshkovitz S, Schwartz S, Salmon-Divon M, Ungar L, Osenberg S, Cesarkas K, Jacob-Hirsch J, Amariglio N, Kupiec M, Sorek R, Rechavi G. Nature. 2012 Apr 29;485(7397):201-6.

N6-methyladenosine-dependent regulation of messenger RNA stability. - N6-methyladenosine-dependent regulation of messenger RNA stability.

Wang X, Lu Z, Gomez A, Hon GC, Yue Y, Han D, Fu Y, Parisien M, Dai Q, Jia G, Ren B, Pan T, He C. Nature. 2014 Jan 2;505(7481):117-20.