Anti-MCU antibody produced in rabbit

• Supplier: Sigma-Aldrich
• Catalog: HPA016480
• Prices: $429.00
• Sizes: 100 µl
• Host: Rabbit
• Clonality: Polyclonal
• Applications: IHC-P ICC/IF
• Species Reactivities: Human
• Antigen: Coiled-coil domain-containing protein 109A recombinant protein epitope signature tag (PrEST)
• Description: Rabbit Polyclonal
• Gene: MCU
• Conjugate: unconjugated

Product images

Immunohistochemistry
Anti-CCDC109A: Cat. No. HPA016480: Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Immunofluorescence
Anti-MCU: Cat. No. HPA016480: Immunofluorescent staining of human cell line U-2 OS shows positivity in mitochondria.

Product References

Integrative genomics identifies MCU as an essential component of the - Integrative genomics identifies MCU as an essential component of the

Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, Bao XR, Strittmatter L, Goldberger O, Bogorad RL, Koteliansky V, Mootha VK. Nature. 2011 Jun 19;476(7360):341-5.

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is - Mitochondrial calcium uniporter Mcu controls excitotoxicity and is

Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE. Nat Commun. 2013;4:2034.

The physiological role of mitochondrial calcium revealed by mice lacking the - The physiological role of mitochondrial calcium revealed by mice lacking the

Pan X, Liu J, Nguyen T, Liu C, Sun J, Teng Y, Fergusson MM, Rovira II, Allen M, Springer DA, Aponte AM, Gucek M, Balaban RS, Murphy E, Finkel T. Nat Cell Biol. 2013 Dec;15(12):1464-72.

Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to - Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to

Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R, Duchen MR, Muntoni F, Sheridan E. Nat Genet. 2014 Feb;46(2):188-93.