Human Reg4 Antibody
| Name | Human Reg4 Antibody |
|---|---|
| Supplier | R&D Systems |
| Catalog | AF1379 |
| Prices | $99.00, $359.00 |
| Sizes | 25 µg, 100 µg |
| Host | Goat |
| Isotype | IgG |
| Applications | IHC WB |
| Species Reactivities | Human |
| Antigen | E. coli -derived recombinant human Reg4 Asp23-Pro158 Accession # Q9BYZ8 |
| Purity/Format | Antigen Affinity-purified |
| Description | Goat |
| Gene | REG4 |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Reg4 in Human Colon Cancer Tissue. Reg4 was detected in immersion fixed paraffin-embedded sections of human colon cancer tissue using Goat Anti-Human Reg4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1379) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013 ). Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008 ) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections .
Product References
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem - Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem
Sasaki N, Sachs N, Wiebrands K, Ellenbroek SI, Fumagalli A, Lyubimova A, Begthel H, van den Born M, van Es JH, Karthaus WR, Li VS, Lopez-Iglesias C, Peters PJ, van Rheenen J, van Oudenaarden A, Clevers H. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5399-407. doi:
RNA sequencing of sessile serrated colon polyps identifies differentially - RNA sequencing of sessile serrated colon polyps identifies differentially
Delker DA, McGettigan BM, Kanth P, Pop S, Neklason DW, Bronner MP, Burt RW, Hagedorn CH. PLoS One. 2014 Feb 12;9(2):e88367.
REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer - REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer
Rafa L, Dessein AF, Devisme L, Buob D, Truant S, Porchet N, Huet G, Buisine MP, Lesuffleur T. Int J Oncol. 2010 Mar;36(3):689-98.
Reg IV is a serum biomarker for gastric cancer patients and predicts response to - Reg IV is a serum biomarker for gastric cancer patients and predicts response to
Mitani Y, Oue N, Matsumura S, Yoshida K, Noguchi T, Ito M, Tanaka S, Kuniyasu H, Kamata N, Yasui W. Oncogene. 2007 Jun 28;26(30):4383-93. Epub 2007 Jan 22.