Anti-DR5 antibody
| Name | Anti-DR5 antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab8416 |
| Prices | $400.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC-P WB ICC/IF ICC/IF |
| Species Reactivities | Mouse, Rat, Human |
| Antigen | Synthetic peptide: KWVNKTGRDASVHTLLDALE , corresponding to amino acids 388-407 of Human DR5 (Peptide available as ab8449 |
| Blocking Peptide | Human DR5 peptide |
| Description | Rabbit Polyclonal |
| Gene | TNFRSF10B |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
The image above is a xenograph of human cancer cells implanted into a nude mouse and allowed to grow for about three weeks. Notice only the human cancer cells expressed this antigen. This picture was kindly submitted as part of the reveiw by Dean Wilkie.
All lanes : Anti-DR5 antibody (ab8416) at 1/500 dilutionLane 1 : HeLa whole cell lysateLane 2 : K562 whole cell lysate
ab8416 at 5µg/ml staining DR5 in Hela cells by ICC/IF
Product References
Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation - Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation
Akram KM, Lomas NJ, Forsyth NR, Spiteri MA. Int J Clin Exp Pathol. 2014 Jan 15;7(2):552-64. eCollection 2014.
Epigenetic silencing of apoptosis-inducing gene expression can be efficiently - Epigenetic silencing of apoptosis-inducing gene expression can be efficiently
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Apoptosis induction by SAHA in cutaneous T-cell lymphoma cells is related to - Apoptosis induction by SAHA in cutaneous T-cell lymphoma cells is related to
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Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death - Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death
Dolloff NG, Mayes PA, Hart LS, Dicker DT, Humphreys R, El-Deiry WS. Sci Transl Med. 2011 Jun 8;3(86):86ra50.
Pigment epithelium-derived factor (PEDF) promotes tumor cell death by inducing - Pigment epithelium-derived factor (PEDF) promotes tumor cell death by inducing
Ho TC, Chen SL, Shih SC, Chang SJ, Yang SL, Hsieh JW, Cheng HC, Chen LJ, Tsao YP. J Biol Chem. 2011 Oct 14;286(41):35943-54.
GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis. - GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis.
Kyronlahti A, Kauppinen M, Lind E, Unkila-Kallio L, Butzow R, Klefstrom J, Wilson DB, Anttonen M, Heikinheimo M. Endocr Relat Cancer. 2010 Jul 28;17(3):709-17.
alpha-TEA-induced death receptor dependent apoptosis involves activation of acid - alpha-TEA-induced death receptor dependent apoptosis involves activation of acid
Li J, Yu W, Tiwary R, Park SK, Xiong A, Sanders BG, Kline K. Cancer Cell Int. 2010 Oct 25;10:40.
The contact allergen nickel sensitizes primary human endothelial cells and - The contact allergen nickel sensitizes primary human endothelial cells and
Schmidt M, Hupe M, Endres N, Raghavan B, Kavuri S, Geserick P, Goebeler M, Leverkus M. J Cell Mol Med. 2010 Jun;14(6B):1760-76.
DR5 and DcR2 are expressed in human lumbar intervertebral discs. - DR5 and DcR2 are expressed in human lumbar intervertebral discs.
Chen B, Ma B, Yang S, Xing X, Gu R, Hu Y. Spine (Phila Pa 1976). 2009 Sep 1;34(19):E677-81. doi:
Increased p53 level, Bax/Bcl-x(L) ratio, and TRAIL receptor expression in human - Increased p53 level, Bax/Bcl-x(L) ratio, and TRAIL receptor expression in human
Morissette MC, Vachon-Beaudoin G, Parent J, Chakir J, Milot J. Am J Respir Crit Care Med. 2008 Aug 1;178(3):240-7. doi: