neurog1

Gene Symbol neurog1
Entrez Gene 30239
Alt Symbol cb260, chunp6899, neurod3, ngn1, ngr1, zNgn1
Species Zebrafish
Gene Type protein-coding
Description neurogenin 1
Other Description NGN-1|Zath4c|neurogenic differentiation 3|neurogenic differentiation factor 3|neurogenin-1|neurogenin-related protein 1
Swissprots O42606
Accessions AAB70528 O42606 AF024535 AAB82271 AF036149 AAB88821 BC056575 AAH56575 BC066427 AAH66427 U94588 AAD09254 NM_131041 NP_571116
Function Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon- Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specification of dopaminergic progenitor cells. May be involved in maintaining rhombomere boundaries in the hindbrain. {ECO:0000250, ECO:0000269|PubMed:12015292, ECO:0000269|PubMed:12413897, ECO:0000269|PubMed:12702659, ECO:0000269|PubMed:15659486, ECO:0000269|PubMed:16549779, ECO:0000269|PubMed:9409673, ECO:0000269|PubMed:9469669}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Embryonic nervous system. Expressed transiently in neurogenic placodes prior to delamination and formation of cranial ganglia. Expressed early (6-somite stage) in Rohon-Beard spinal sensory neurons and later in neural crest- derived dorsal root ganglion neurons. At 24 hours post- fertilization (hpf), expressed in specific regions of the brain and spinal cord. In hindbrain, expressed in presumptive neuroblasts adjacent to the rhombomere boundaries. In basal forebrain, expressed in dopaminergic progenitor cells. {ECO:0000269|PubMed:12015292, ECO:0000269|PubMed:12413897, ECO:0000269|PubMed:15659486, ECO:0000269|PubMed:16549779, ECO:0000269|PubMed:9409673, ECO:0000269|PubMed:9469669, ECO:0000269|PubMed:9733104}.

Neurogenin 1 (zebrafish) blocking peptide - GTX48503-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Zebrafish

Neurogenin 1 Peptide - 46-873P from ProSci

Category Peptide

Recombinant Zebrafish NEUROG1 - NEUROG1-8669Z from Creative Biomart

Category Protein
Source Mammalian Cells
Species Zebrafish

Recombinant Danio rerio Neurogenin-1(neurog1) - CSB-YP015730DIL CSB-EP015730DIL CSB-BP015730DIL CSB-MP015730DIL from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Zebrafish

Neurogenin 1 , Peptide - MBS425604 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Zebrafish

Neurogenin-1 (neurog1), Recombinant Protein - MBS1023530 from MyBioSource

Category Protein
Prices $960.00, $960.00, $1,180.00, $1,180.00, $1,435.00, $1,435.00, $1,900.00, $1,900.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Zebrafish
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