| Gene Symbol |
RAP1GAP2
|
| Entrez Gene |
23108
|
| Alt Symbol |
GARNL4, RAP1GA3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAP1 GTPase activating protein 2
|
| Other Description |
GTPase activating RANGAP domain-like 4|GTPase activating Rap/RanGAP domain-like 4|GTPase-activating Rap/Ran-GAP domain-like protein 4|rap1 GTPase-activating protein 2
|
| Swissprots |
Q6ZVF0 Q684P5 B2RTY5 Q684P4 Q9UPW2 Q6AI00
|
| Accessions |
EAW90526 EAW90527 EAW90528 EAW90529 Q684P5 AB028962 BAA82991 AJ628446 CAF31652 AJ628447 CAF31653 AK000478 AK124640 BAC85912 AK127021 BC037493 BC140870 AAI40871 BC140871 AAI40872 BE208439 BU629928 CR627427 CAH10514 DN831680 XM_005256541 XP_005256598 XM_005256542 XP_005256599 XM_006721477 XP_006721540 XM_011523738 XP_011522040 XM_011523739 XP_011522041 XM_011523740 XP_011522042 XM_011523741 XP_011522043 XM_011523742 XP_011522044 XM_011523743 XP_011522045 XM_011523744 XP_011522046 XM_011523745 XP_011522047 NM_001100398 NP_001093868 NM_015085 NP_055900
|
| Function |
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000269|PubMed:15632203}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15632203}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:15632203}.
|
| Tissue Specificity |
Isoform 1 and isoform 2 are expressed in platelets with isoform 2 being the predominant form. Expressed in lymphocytes, heart, testis and pancreas. {ECO:0000269|PubMed:15632203}.
|
![Western Blot: RAP1GAP2 Overexpression Lysate (Adult Normal) [NBP2-07198] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAP1GAP2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4882_RAP1GAP2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07198-img0001.jpg)