| Gene Symbol | erg9 |
|---|---|
| Entrez Gene | 2541110 |
| Alt Symbol | - |
| Species | S. pombe |
| Gene Type | protein-coding |
| Description | squalene synthase Erg9 (predicted) |
| Other Description | - |
| Swissprots | P36596 |
| Accessions | CAA22809 P36596 NM_001021271 NP_595363 |
| Function | Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol. {ECO:0000269|PubMed:8474436}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:17016471}; Multi- pass membrane protein {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:17016471}. |
| Top Pathways | Sesquiterpenoid and triterpenoid biosynthesis, Steroid biosynthesis |