| Gene Symbol |
erg9
|
| Entrez Gene |
2541110
|
| Alt Symbol |
-
|
| Species |
S. pombe
|
| Gene Type |
protein-coding
|
| Description |
squalene synthase Erg9 (predicted)
|
| Other Description |
-
|
| Swissprots |
P36596
|
| Accessions |
CAA22809 P36596 NM_001021271 NP_595363
|
| Function |
Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol. {ECO:0000269|PubMed:8474436}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:17016471}; Multi- pass membrane protein {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:17016471}.
|
| Top Pathways |
Sesquiterpenoid and triterpenoid biosynthesis, Steroid biosynthesis
|