Gene Symbol | MUT |
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Entrez Gene | 4594 |
Alt Symbol | MCM |
Species | Human |
Gene Type | protein-coding |
Description | methylmalonyl CoA mutase |
Other Description | methylmalonyl Coenzyme A mutase|methylmalonyl-CoA isomerase|methylmalonyl-CoA mutase, mitochondrial |
Swissprots | Q5SYZ3 P22033 Q9UD64 Q96B11 A8K953 |
Accessions | AAA99226 AGL09917 AGL09918 AGL09919 AGL09920 AGL09921 AGL09922 AGL09923 AGL09924 AGL09925 AGL09926 AGL09927 AGL09928 AGL09929 AGL09930 AGL09931 AGL09932 AGL09933 AGL09934 AGL09935 AJC52540 AJC52541 EAX04329 EAX04330 EAX04331 P22033 AB208845 BAD92082 AK292568 BAF85257 AK312611 BAG35498 BC016282 AAH16282 BT007434 AAP36102 BX647789 CA444307 DA777441 DB290266 KF030882 AGU16980 M65131 AAA59569 XM_005249143 XP_005249200 NM_000255 NP_000246 |
Function | Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species. |
Subcellular Location | Mitochondrion matrix. |
Top Pathways | Glyoxylate and dicarboxylate metabolism, Carbon metabolism, Valine, leucine and isoleucine degradation, Propanoate metabolism |
MUT CRISPR/Cas9 KO Plasmid (h) - sc-406555 from Santa Cruz Biotechnology
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MUT HDR Plasmid (h) - sc-406555-HDR from Santa Cruz Biotechnology
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MUT Double Nickase Plasmid (h) - sc-406555-NIC from Santa Cruz Biotechnology
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MUT Double Nickase Plasmid (h2) - sc-406555-NIC-2 from Santa Cruz Biotechnology
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MUT CRISPR Activation Plasmid (h) - sc-406555-ACT from Santa Cruz Biotechnology
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MUT CRISPR Activation Plasmid (h2) - sc-406555-ACT-2 from Santa Cruz Biotechnology
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MUT Lentiviral Activation Particles (h) - sc-406555-LAC from Santa Cruz Biotechnology
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MUT Lentiviral Activation Particles (h2) - sc-406555-LAC-2 from Santa Cruz Biotechnology
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MUT siRNA (h) - sc-95089 from Santa Cruz Biotechnology
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MUT shRNA Plasmid (h) - sc-95089-SH from Santa Cruz Biotechnology
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MUT shRNA (h) Lentiviral Particles - sc-95089-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU088521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14772 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14772 from Sigma-Aldrich
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MUT siRNA (Human) - CRH3026 from Cohesion Biosciences
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Methylmalonyl Coenzyme A mutase RNAi - H00004594-R01 from Novus Biologicals
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MUT CRISPR/Cas9 KO Plasmid (h2) - sc-406555-KO-2 from Santa Cruz Biotechnology
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MUT HDR Plasmid (h2) - sc-406555-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human MUT (NM_000255.3) - SHH347208 from Creative biogene
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Human MUT siRNA - orb263528 from Biorbyt
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MUT shRNA Plasmid (Human) - CHH3026 from Cohesion Biosciences
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MUT miRNA 3'UTR clone - MiUTR3H-10377 from Creative biogene
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