| Gene Symbol |
HIGD1A
|
| Entrez Gene |
25994
|
| Alt Symbol |
HIG1, RCF1a
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
HIG1 hypoxia inducible domain family, member 1A
|
| Other Description |
HIG1 domain family member 1A, mitochondrial|HIG1 domain family, member 1A|RCF1 homolog A|hypoxia inducible gene 1|hypoxia-inducible gene 1 protein
|
| Swissprots |
Q9UFZ2 Q9Y241
|
| Accessions |
EAW64673 EAW64674 EAW64675 EAW64676 EAW64677 Q9Y241 AF077034 AAD27767 AF145385 AAD33954 AK225461 AK225571 AK311815 BAG34758 AL110233 CAB53686 AM393830 CAL38705 BC000601 AAH00601 BC009583 AAH09583 BC009594 AAH09594 BC070277 AAH70277 BG708126 BM983292 BM983580 BP208784 BP370118 CR457385 CAG33666 DA428926 NM_001099668 NP_001093138 NM_001099669 NP_001093139 NM_014056 NP_054775
|
| Function |
Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes. {ECO:0000269|PubMed:22342701}.
|
| Subcellular Location |
Mitochondrion membrane {ECO:0000255|PROSITE- ProRule:PRU00836, ECO:0000269|PubMed:22342701}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00836, ECO:0000269|PubMed:22342701}. Mitochondrion inner membrane {ECO:0000305|PubMed:22342701}.
|
![Western Blot: HIGD1A Overexpression Lysate (Adult Normal) [NBL1-11542] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HIGD1A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3754_HIGD1A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11542-img0002.jpg)
![Western Blot: HIGD1A Overexpression Lysate (Adult Normal) [NBP2-09315] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HIGD1A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1227_HIGD1A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09315-img0001.jpg)