Gene Symbol | KIF5C |
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Entrez Gene | 3800 |
Alt Symbol | CDCBM2, KINN, NKHC, NKHC-2, NKHC2 |
Species | Human |
Gene Type | protein-coding |
Description | kinesin family member 5C |
Other Description | kinesin heavy chain isoform 5C|kinesin heavy chain neuron-specific 2|kinesin, heavy chain, neuron-specific |
Swissprots | Q2YDC5 O60282 O95079 |
Accessions | AAX82030 AAX82035 AAX82036 AAY24013 EAX11544 O60282 AA602178 AB011103 BAA25457 AB073396 BAE45725 AB209191 BAD92428 AF010146 AAD01436 AK126689 AL050070 AL117393 CAB55895 AW162840 BC002721 AAH02721 BC017298 AAH17298 BC025961 AAH25961 BC110287 AAI10288 BC127772 AAI27773 DA085551 DA501487 HY003338 XM_011511157 XP_011509459 XR_922926 NM_004522 NP_004513 NR_111932 |
Function | Mediates dendritic trafficking of mRNAs (By similarity). Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000305}. |
Tissue Specificity | Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary. |
Top Pathways | Dopaminergic synapse |
NKHC2 CRISPR/Cas9 KO Plasmid (h) - sc-408029 from Santa Cruz Biotechnology
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NKHC2 HDR Plasmid (h) - sc-408029-HDR from Santa Cruz Biotechnology
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NKHC2 Double Nickase Plasmid (h) - sc-408029-NIC from Santa Cruz Biotechnology
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NKHC2 Double Nickase Plasmid (h2) - sc-408029-NIC-2 from Santa Cruz Biotechnology
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NKHC2 CRISPR Activation Plasmid (h) - sc-408029-ACT from Santa Cruz Biotechnology
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NKHC2 CRISPR Activation Plasmid (h2) - sc-408029-ACT-2 from Santa Cruz Biotechnology
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NKHC2 Lentiviral Activation Particles (h) - sc-408029-LAC from Santa Cruz Biotechnology
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NKHC2 Lentiviral Activation Particles (h2) - sc-408029-LAC-2 from Santa Cruz Biotechnology
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NKHC2 siRNA (h) - sc-61203 from Santa Cruz Biotechnology
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NKHC2 shRNA Plasmid (h) - sc-61203-SH from Santa Cruz Biotechnology
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NKHC2 shRNA (h) Lentiviral Particles - sc-61203-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU089971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11206 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11206 from Sigma-Aldrich
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KIF5C siRNA (Human) - CRH2571 from Cohesion Biosciences
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shRNA set against Human KIF5C (NM_004522.2) - SHH325371 from Creative biogene
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KIF5C shRNA Plasmid (Human) - CHH2571 from Cohesion Biosciences
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KIF5C miRNA 3'UTR clone - MiUTR4H-TG11593 from Creative biogene
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