Gene Symbol | B4galnt1 |
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Entrez Gene | 14421 |
Alt Symbol | 4933429D13Rik, Gal-NAc-T, GalNAc-T, GalNAcT, Galgt1, Ggm-2, Ggm2 |
Species | Mouse |
Gene Type | protein-coding |
Description | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
Other Description | (N-acetylneuraminyl)-galactosylglucosylceramide|GM2/GD2 synthase|UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase|beta-1,4 N-acetylgalactosaminyltransferase 1|beta1,4GalNAC-T |
Swissprots | Q09200 |
Accessions | EDL24473 EDL24474 EDL24475 EDL24476 EDL24477 EDL24478 Q09200 AK040324 AK086849 AK144484 BAE25913 BB635804 BC019969 BC022180 AAH22180 BC036996 AAH36996 BC057199 AAH57199 BE996315 L25885 AAA65027 U18975 AAA85496 XM_006513219 XP_006513282 XM_011243369 XP_011241671 NM_001244617 NP_001231546 NM_001244618 NP_001231547 NM_008080 NP_032106 NM_027739 NP_082015 NR_045166 |
Function | Involved in the biosynthesis of gangliosides GM2, GD2 and GA2. |
Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
Tissue Specificity | Most abundant in brain, liver, lung, spleen and testis. |
Top Pathways | Glycosphingolipid biosynthesis - ganglio series |
GM2/GD2 synthase CRISPR/Cas9 KO Plasmid (m) - sc-420474 from Santa Cruz Biotechnology
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GM2/GD2 synthase HDR Plasmid (m) - sc-420474-HDR from Santa Cruz Biotechnology
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GM2/GD2 synthase Double Nickase Plasmid (m) - sc-420474-NIC from Santa Cruz Biotechnology
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GM2/GD2 synthase Double Nickase Plasmid (m2) - sc-420474-NIC-2 from Santa Cruz Biotechnology
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GM2/GD2 synthase CRISPR Activation Plasmid (m) - sc-420474-ACT from Santa Cruz Biotechnology
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GM2/GD2 synthase CRISPR Activation Plasmid (m2) - sc-420474-ACT-2 from Santa Cruz Biotechnology
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GM2/GD2 synthase Lentiviral Activation Particles (m) - sc-420474-LAC from Santa Cruz Biotechnology
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GM2/GD2 synthase Lentiviral Activation Particles (m2) - sc-420474-LAC-2 from Santa Cruz Biotechnology
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GM2/GD2 synthase siRNA (m) - sc-77390 from Santa Cruz Biotechnology
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GM2/GD2 synthase shRNA Plasmid (m) - sc-77390-SH from Santa Cruz Biotechnology
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GM2/GD2 synthase shRNA (m) Lentiviral Particles - sc-77390-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU092731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN27359 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27359 from Sigma-Aldrich
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B4GALNT1 siRNA (Mouse) - CRM1481 from Cohesion Biosciences
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B4GALNT1 - MBS8225231 from MyBioSource
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shRNA set against Mouse B4GALNT1 (NM_008080.5) - SHH244358 from Creative biogene
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GM2/GD2 synthase CRISPR/Cas9 KO Plasmid (m2) - sc-420474-KO-2 from Santa Cruz Biotechnology
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GM2/GD2 synthase HDR Plasmid (m2) - sc-420474-HDR-2 from Santa Cruz Biotechnology
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Mouse B4GALNT1 siRNA - orb280957 from Biorbyt
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B4GALNT1 shRNA Plasmid (Mouse) - CHM1481 from Cohesion Biosciences
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