Gene Symbol | T |
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Entrez Gene | 6862 |
Alt Symbol | SAVA, TFT |
Species | Human |
Gene Type | protein-coding |
Description | T, brachyury homolog (mouse) |
Other Description | T brachyury homolog|brachyury protein|protein T |
Swissprots | Q4KMP4 E7ERD6 O15178 |
Accessions | CBX55887 EAW47538 EAW47539 O15178 AJ001699 CAA04938 BC039877 BC098425 AAH98425 BE785653 BG436736 BU190437 XM_011536080 XP_011534382 XM_011536081 XP_011534383 NM_001270484 NP_001257413 NM_003181 NP_003172 |
Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22611028, ECO:0000269|PubMed:24253444}. |
Tissue Specificity | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level). {ECO:0000269|PubMed:22611028}. |
brachyury CRISPR/Cas9 KO Plasmid (h) - sc-416539 from Santa Cruz Biotechnology
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brachyury HDR Plasmid (h) - sc-416539-HDR from Santa Cruz Biotechnology
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brachyury Double Nickase Plasmid (h) - sc-416539-NIC from Santa Cruz Biotechnology
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brachyury Double Nickase Plasmid (h2) - sc-416539-NIC-2 from Santa Cruz Biotechnology
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brachyury CRISPR Activation Plasmid (h) - sc-416539-ACT from Santa Cruz Biotechnology
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brachyury CRISPR Activation Plasmid (h2) - sc-416539-ACT-2 from Santa Cruz Biotechnology
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brachyury Lentiviral Activation Particles (h) - sc-416539-LAC from Santa Cruz Biotechnology
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brachyury Lentiviral Activation Particles (h2) - sc-416539-LAC-2 from Santa Cruz Biotechnology
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brachyury siRNA (h) - sc-29820 from Santa Cruz Biotechnology
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brachyury shRNA Plasmid (h) - sc-29820-SH from Santa Cruz Biotechnology
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brachyury shRNA (h) Lentiviral Particles - sc-29820-V from Santa Cruz Biotechnology
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Brachyury RNAi - H00006862-R01V from Novus Biologicals
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Brachyury RNAi - H00006862-R01 from Novus Biologicals
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MISSION® esiRNA - EHU149771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20936 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20936 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05909 from Sigma-Aldrich
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T siRNA (Human) - CRH4692 from Cohesion Biosciences
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T - MBS8225872 from MyBioSource
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T shRNA Plasmid (Human) - CHH4692 from Cohesion Biosciences
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T miRNA 3'UTR clone - MiUTR4H-TG12569 from Creative biogene
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