| Gene Symbol | MYO19 |
|---|---|
| Entrez Gene | 80179 |
| Alt Symbol | MYOHD1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | myosin XIX |
| Other Description | myosin head domain containing 1|myosin head domain-containing protein 1|myosin-XIX|unconventional myosin-XIX |
| Swissprots | Q59GS4 Q9H5X2 Q96H55 |
| Accessions | CCQ43728 EAW57556 EAW57557 EAW57558 EAW57559 EAW57560 EAW57561 Q96H55 AA631248 AB209035 BAD92272 AK026518 BAB15495 AK293903 BAH11623 AK299802 BAG61677 AK304073 BAG64980 AL133017 AY545559 AAS50154 BC008900 AAH08900 BC036325 BM661625 BM921100 BU543266 CD656712 XM_006725351 XP_006725414 XM_006725354 XP_006725417 XM_006725355 XP_006725418 XM_011525285 XP_011523587 XM_011525286 XP_011523588 XM_011525287 XP_011523589 XM_011525288 XP_011523590 XM_011525289 XP_011523591 XM_011525290 XP_011523592 XM_011525291 XP_011523593 XM_011525292 XP_011523594 XM_011525293 XP_011523595 XM_011546836 XP_011545138 XM_011546837 XP_011545139 XM_011546838 XP_011545140 XM_011546839 XP_011545141 XM_011546840 XP_011545142 XM_011546841 XP_011545143 XM_011546842 XP_011545144 XM_011546843 XP_011545145 NM_001033579 NM_001033580 NP_001028752 NM_001163735 NP_001157207 NM_025109 NP_079385 |
| Function | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility. {ECO:0000269|PubMed:19932026}. |
| Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19932026}. Mitochondrion outer membrane {ECO:0000269|PubMed:19932026}. Note=Probably associated with the outer membrane via its N-terminal mitochondrial targeting region. |
| Tissue Specificity | Widely expressed in multiple tissues and cell lines. {ECO:0000269|PubMed:19932026}. |
Myosin-XIX CRISPR/Cas9 KO Plasmid (h) - sc-413355 from Santa Cruz Biotechnology
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Myosin-XIX HDR Plasmid (h) - sc-413355-HDR from Santa Cruz Biotechnology
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Myosin-XIX Double Nickase Plasmid (h) - sc-413355-NIC from Santa Cruz Biotechnology
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Myosin-XIX Double Nickase Plasmid (h2) - sc-413355-NIC-2 from Santa Cruz Biotechnology
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Myosin-XIX CRISPR Activation Plasmid (h) - sc-413355-ACT from Santa Cruz Biotechnology
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Myosin-XIX CRISPR Activation Plasmid (h2) - sc-413355-ACT-2 from Santa Cruz Biotechnology
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Myosin-XIX Lentiviral Activation Particles (h) - sc-413355-LAC from Santa Cruz Biotechnology
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Myosin-XIX Lentiviral Activation Particles (h2) - sc-413355-LAC-2 from Santa Cruz Biotechnology
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Myosin XIX siRNA (h) - sc-93640 from Santa Cruz Biotechnology
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Myosin XIX shRNA Plasmid (h) - sc-93640-SH from Santa Cruz Biotechnology
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Myosin XIX shRNA (h) Lentiviral Particles - sc-93640-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU132061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14851 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05475 from Sigma-Aldrich
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MYO19 siRNA (Human) - CRJ2788 from Cohesion Biosciences
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shRNA set against Human MYO19 (NM_025109.5) - SHH348132 from Creative biogene
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MYO19 shRNA Plasmid (Human) - CHJ2788 from Cohesion Biosciences
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MYO19 miRNA 3'UTR clone - MiUTR3H-15556 from Creative biogene
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MYO19 miRNA 3'UTR clone - MiUTR3H-15557 from Creative biogene
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MYO19 miRNA 3'UTR clone - MiUTR3H-15558 from Creative biogene
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