Gene Symbol |
ATP6V1H
|
Entrez Gene |
397472
|
Alt Symbol |
V-ATPASE
|
Species |
Pig
|
Gene Type |
protein-coding
|
Description |
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
|
Other Description |
54 kDa vacuolar H(+)-ATPase subunit|V-ATPase 50/57 kDa subunits|V-ATPase subunit H|V-type proton ATPase subunit H|Vacuolar proton pump subunit H|vacuolar proton pump subunit SFD
|
Swissprots |
Q9XSM4 Q9TVC1 Q9XSM5
|
Accessions |
CAB39537 Q9TVC1 AJ223757 CAB39532 AJ223758 CAB39533 AK236336 AK396440 XM_005653063 XP_005653120 NM_214240 NP_999405
|
Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes (By similarity). {ECO:0000250}.
|
Top Pathways |
Lysosome, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle, Tuberculosis
|