Gene Symbol |
PSMD9
|
Entrez Gene |
5715
|
Alt Symbol |
Rpn4, p27
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
|
Other Description |
26S proteasome non-ATPase regulatory subunit 9|26S proteasome regulatory subunit p27|homolog of rat Bridge 1|proteasome 26S non-ATPase regulatory subunit 9
|
Swissprots |
G3V1Q6 O00233 Q9BQ42 B2RD35
|
Accessions |
CAH05702 CAR82351 EAW98293 EAW98294 EAW98295 EAW98296 EAW98297 O00233 AK055339 AK315389 BAG37782 BC002383 AAH02383 BC004184 AAH04184 BC004213 AAH04213 BI832046 BM850893 BU726372 BU956605 CB111716 CN260241 DQ893594 ABM84520 EU831432 ACE87119 EU831524 ACE86443 NM_001261400 NP_001248329 NM_002813 NP_002804 NR_048555
|
Function |
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process. {ECO:0000269|PubMed:19490896}.
|
Tissue Specificity |
Expressed in all tissues tested, highly expressed in liver and kidney.
|