Gene Symbol | PCYOX1 |
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Entrez Gene | 51449 |
Alt Symbol | PCL1 |
Species | Human |
Gene Type | protein-coding |
Description | prenylcysteine oxidase 1 |
Other Description | prenylcysteine lyase |
Swissprots | B7Z9P8 O94982 Q8N4N5 Q96QM8 B2RB14 Q9UHG3 |
Accessions | AAX81995 AAX93194 EAW99819 Q9UHG3 AB020715 BAA74931 AF181490 AAF16937 AK225302 AK296478 BAH12368 AK303043 BAH13888 AK314453 BAG37061 AK316013 BAH14384 AY359063 AAQ89422 BC007029 AAH07029 BC022259 BC033815 AAH33815 BC051891 AAH51891 DC417137 DQ890801 ABM81727 DQ893956 ABM84882 NM_016297 NP_057381 |
Function | Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine. |
Subcellular Location | Lysosome. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Terpenoid backbone biosynthesis |
PCYOX1 CRISPR/Cas9 KO Plasmid (h) - sc-407075 from Santa Cruz Biotechnology
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PCYOX1 HDR Plasmid (h) - sc-407075-HDR from Santa Cruz Biotechnology
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PCYOX1 Double Nickase Plasmid (h) - sc-407075-NIC from Santa Cruz Biotechnology
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PCYOX1 Double Nickase Plasmid (h2) - sc-407075-NIC-2 from Santa Cruz Biotechnology
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PCYOX1 CRISPR Activation Plasmid (h) - sc-407075-ACT from Santa Cruz Biotechnology
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PCYOX1 CRISPR Activation Plasmid (h2) - sc-407075-ACT-2 from Santa Cruz Biotechnology
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PCYOX1 Lentiviral Activation Particles (h) - sc-407075-LAC from Santa Cruz Biotechnology
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PCYOX1 Lentiviral Activation Particles (h2) - sc-407075-LAC-2 from Santa Cruz Biotechnology
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PCYOX1 siRNA (h) - sc-76093 from Santa Cruz Biotechnology
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PCYOX1 shRNA Plasmid (h) - sc-76093-SH from Santa Cruz Biotechnology
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PCYOX1 shRNA (h) Lentiviral Particles - sc-76093-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU016731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16507 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16507 from Sigma-Aldrich
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PCYOX1 siRNA (Human) - CRH9770 from Cohesion Biosciences
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PCYOX1 RNAi - H00051449-R01 from Novus Biologicals
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shRNA set against Human PCYOX1(NM_016297.3) - SHR098312 from Creative biogene
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PCYOX1 shRNA Plasmid (Human) - CHH9770 from Cohesion Biosciences
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PCYOX1 miRNA 3'UTR clone - MiUTR1H-07690 from Creative biogene
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