Gene Symbol | SPRN |
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Entrez Gene | 503542 |
Alt Symbol | SHADOO, SHO, bA108K14.1 |
Species | Human |
Gene Type | protein-coding |
Description | shadow of prion protein homolog (zebrafish) |
Other Description | hypothetical protein BC004409|protein shadoo|shadow of prion protein |
Swissprots | Q5BIV9 |
Accessions | CAG34288 Q5BIV9 AK123191 AW293555 BC040198 AAH40198 CD580523 XM_005252684 XP_005252741 NM_001012508 NP_001012526 |
Function | Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
Tissue Specificity | Mainly expressed in brain. In brain, it is expressed in hippocampus. {ECO:0000269|PubMed:14527721}. |
SPRN CRISPR/Cas9 KO Plasmid (h) - sc-407259 from Santa Cruz Biotechnology
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SPRN HDR Plasmid (h) - sc-407259-HDR from Santa Cruz Biotechnology
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SPRN Double Nickase Plasmid (h) - sc-407259-NIC from Santa Cruz Biotechnology
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SPRN Double Nickase Plasmid (h2) - sc-407259-NIC-2 from Santa Cruz Biotechnology
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SPRN CRISPR Activation Plasmid (h) - sc-407259-ACT from Santa Cruz Biotechnology
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SPRN CRISPR Activation Plasmid (h2) - sc-407259-ACT-2 from Santa Cruz Biotechnology
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SPRN Lentiviral Activation Particles (h) - sc-407259-LAC from Santa Cruz Biotechnology
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SPRN Lentiviral Activation Particles (h2) - sc-407259-LAC-2 from Santa Cruz Biotechnology
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SPRN siRNA (h) - sc-90403 from Santa Cruz Biotechnology
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SPRN shRNA Plasmid (h) - sc-90403-SH from Santa Cruz Biotechnology
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SPRN shRNA (h) Lentiviral Particles - sc-90403-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20516 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20516 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11587 from Sigma-Aldrich
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SPRN siRNA (Human) - CRJ8377 from Cohesion Biosciences
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SPRN - MBS8212085 from MyBioSource
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SPRN CRISPR/Cas9 KO Plasmid (h2) - sc-407259-KO-2 from Santa Cruz Biotechnology
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SPRN HDR Plasmid (h2) - sc-407259-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human SPRN (NM_001012508.3) - SHH417212 from Creative biogene
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shRNA set against Human SPRN(NM_001012508.3) - SHL030684 from Creative biogene
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SPRN shRNA Plasmid (Human) - CHJ8377 from Cohesion Biosciences
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SPRN miRNA 3'UTR clone - MiUTR1H-09869 from Creative biogene
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