| Gene Symbol |
GABRE
|
| Entrez Gene |
2564
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
gamma-aminobutyric acid (GABA) A receptor, epsilon
|
| Other Description |
GABA(A) receptor subunit epsilon|GABA(A) receptor, epsilon|gamma-aminobutyric acid receptor subunit epsilon
|
| Swissprots |
Q99520 O15346 Q6PCD2 O15345 E7ET93 P78334
|
| Accessions |
AAB94645 CAA70903 EAW99414 EAW99415 EAW99416 EAW99417 EAW99418 EAW99419 P78334 AF086385 AK124085 AK299174 BAG61220 AK303072 BAG64188 AL603607 BC026337 AAH26337 BC047108 AAH47108 BC059376 AAH59376 HQ448560 ADQ33039 U66661 AAB49284 U92285 Y07637 CAA68914 Y09765 CAA70904 XM_006724813 XP_006724876 XM_011531135 XP_011529437 XM_011531136 XP_011529438 XM_011531137 XP_011529439 XM_011531138 XP_011529440 XM_011531139 XP_011529441 XM_011531140 XP_011529442 NM_004961 NP_004952 NM_021984 NM_021987 NM_021990
|
| Function |
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in many tissues. Highest levels of expression in adult heart and placenta.
|
| Top Pathways |
GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction
|
![Western Blot: GABA Receptor Epsilon Overexpression Lysate (Adult Normal) [NBL1-10924] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GABA Receptor Epsilon.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1819_GABA%2520Receptor%2520Epsilon%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10924-img0002.jpg)