Gene Symbol | ADCYAP1 |
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Entrez Gene | 116 |
Alt Symbol | PACAP |
Species | Human |
Gene Type | protein-coding |
Description | adenylate cyclase activating polypeptide 1 (pituitary) |
Other Description | pituitary adenylate cyclase-activating polypeptide|prepro-PACAP |
Swissprots | B2R7N4 P18509 Q52LQ0 |
Accessions | AAT92256 AAT92261 CAA42962 EAX01706 P18509 AB537500 BAJ09301 AK294233 BAH11708 AK313050 BAG35881 BC093837 AAH93837 BC101803 AAI01804 DA145895 DC320719 DN991692 S83513 AAB21470 XM_005258081 XP_005258138 NM_001099733 NP_001093203 NM_001117 NP_001108 |
Function | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. {ECO:0000269|PubMed:11175907, ECO:0000269|PubMed:23800469}. |
Subcellular Location | Secreted. |
PACAP CRISPR/Cas9 KO Plasmid (h) - sc-402741 from Santa Cruz Biotechnology
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PACAP HDR Plasmid (h) - sc-402741-HDR from Santa Cruz Biotechnology
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PACAP Double Nickase Plasmid (h) - sc-402741-NIC from Santa Cruz Biotechnology
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PACAP Double Nickase Plasmid (h2) - sc-402741-NIC-2 from Santa Cruz Biotechnology
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PACAP CRISPR Activation Plasmid (h) - sc-402741-ACT from Santa Cruz Biotechnology
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PACAP CRISPR Activation Plasmid (h2) - sc-402741-ACT-2 from Santa Cruz Biotechnology
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PACAP Lentiviral Activation Particles (h) - sc-402741-LAC from Santa Cruz Biotechnology
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PACAP Lentiviral Activation Particles (h2) - sc-402741-LAC-2 from Santa Cruz Biotechnology
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PACAP siRNA (h) - sc-39530 from Santa Cruz Biotechnology
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PACAP shRNA Plasmid (h) - sc-39530-SH from Santa Cruz Biotechnology
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PACAP shRNA (h) Lentiviral Particles - sc-39530-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN2868 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2868 from Sigma-Aldrich
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ADCYAP1 siRNA (Human) - CRH0078 from Cohesion Biosciences
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ADCYAP1 - MBS8219047 from MyBioSource
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shRNA set against Human ADCYAP1 (NM_001117.3) - SHH232278 from Creative biogene
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shRNA set against Human ADCYAP1(NM_001117.3) - SHG041599 from Creative biogene
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Human ADCYAP1 siRNA - orb260580 from Biorbyt
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ADCYAP1 shRNA Plasmid (Human) - CHH0078 from Cohesion Biosciences
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ADCYAP1 miRNA 3'UTR clone - MiUTR1H-00190 from Creative biogene
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