Gene Symbol | MLXIPL |
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Entrez Gene | 51085 |
Alt Symbol | CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH, bHLHd14 |
Species | Human |
Gene Type | protein-coding |
Description | MLX interacting protein-like |
Other Description | MLX-interacting protein-like|Mlx interactor|WS basic-helix-loop-helix leucine zipper protein|Williams Beuren syndrome chromosome region 14|Williams-Beuren syndrome chromosome region 14 protein 1|Williams-Beuren syndrome chromosome region 14 protein 2|carbohydrate response element binding protein|carbohydrate-responsive element-binding protein|class D basic helix-loop-helix protein 14|williams-Beuren syndrome chromosomal region 14 protein |
Swissprots | C5HU04 Q9BY05 C5HU03 Q9BY04 C5HU02 Q9BY03 Q9BY06 Q9NP71 Q96E48 Q9Y2P3 |
Accessions | AAF68176 ACS13745 ACS13746 ACS13747 AGR34141 AGR34142 AGR34143 EAW69660 EAW69661 EAW69663 EAW69668 Q9NP71 AF156603 AAF68174 AF245470 AAK20935 AF245471 AAK20936 AF245472 AAK20937 AF245473 AAK20938 AF245474 AAK20939 AK055029 BC012925 AAH12925 XM_011516277 XP_011514579 XM_011516278 XP_011514580 XM_011516279 XP_011514581 XM_011516280 XP_011514582 XM_011516281 XP_011514583 XR_927474 XR_927475 NM_032951 NP_116569 NM_032952 NP_116570 NM_032953 NP_116571 NM_032954 NP_116572 NM_032994 |
Function | Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in liver, heart, kidney, cerebellum and intestinal tissues. |
Top Pathways | Non-alcoholic fatty liver disease (NAFLD) |
ChREBP CRISPR/Cas9 KO Plasmid (h) - sc-401803 from Santa Cruz Biotechnology
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ChREBP HDR Plasmid (h) - sc-401803-HDR from Santa Cruz Biotechnology
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ChREBP Double Nickase Plasmid (h) - sc-401803-NIC from Santa Cruz Biotechnology
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ChREBP Double Nickase Plasmid (h2) - sc-401803-NIC-2 from Santa Cruz Biotechnology
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ChREBP CRISPR Activation Plasmid (h) - sc-401803-ACT from Santa Cruz Biotechnology
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ChREBP CRISPR Activation Plasmid (h2) - sc-401803-ACT-2 from Santa Cruz Biotechnology
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ChREBP Lentiviral Activation Particles (h) - sc-401803-LAC from Santa Cruz Biotechnology
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ChREBP Lentiviral Activation Particles (h2) - sc-401803-LAC-2 from Santa Cruz Biotechnology
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ChREBP siRNA (h) - sc-38617 from Santa Cruz Biotechnology
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ChREBP shRNA Plasmid (h) - sc-38617-SH from Santa Cruz Biotechnology
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ChREBP shRNA (h) Lentiviral Particles - sc-38617-V from Santa Cruz Biotechnology
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CHREBP RNAi - H00051085-R01 from Novus Biologicals
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CHREBP RNAi - H00051085-R02 from Novus Biologicals
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MISSION® esiRNA - EHU094041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14413 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14413 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06233 from Sigma-Aldrich
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MLXIPL siRNA (Human) - CRH9507 from Cohesion Biosciences
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CHREBP RNAi - H00051085-R04 from Novus Biologicals
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CHREBP RNAi - H00051085-R03 from Novus Biologicals
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CHREBP RNAi - H00051085-R05 from Novus Biologicals
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MLXIPL shRNA Plasmid (Human) - CHH9507 from Cohesion Biosciences
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