| Gene Symbol | LOC100328937 |
|---|---|
| Entrez Gene | 100328937 |
| Alt Symbol | CYP1A2, CYPIA2, P450-PM4 |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | cytochrome P450 LM4 |
| Other Description | P450 LM4|P450 isozyme 4|cytochrome P450 1A2|cytochrome P450 isozyme 4|cytochrome P450-PM4 |
| Swissprots | Q29526 P00187 |
| Accessions | P00187 M36538 AAA31437 X05686 CAA29171 X13853 CAA32066 XM_008252401 XP_008250623 XM_008252402 XP_008250624 NM_001171121 NP_001164592 |
| Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. |
| Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Top Pathways | Steroid hormone biosynthesis, Chemical carcinogenesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism |