| Gene Symbol |
LOC100328937
|
| Entrez Gene |
100328937
|
| Alt Symbol |
CYP1A2, CYPIA2, P450-PM4
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450 LM4
|
| Other Description |
P450 LM4|P450 isozyme 4|cytochrome P450 1A2|cytochrome P450 isozyme 4|cytochrome P450-PM4
|
| Swissprots |
Q29526 P00187
|
| Accessions |
P00187 M36538 AAA31437 X05686 CAA29171 X13853 CAA32066 XM_008252401 XP_008250623 XM_008252402 XP_008250624 NM_001171121 NP_001164592
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Top Pathways |
Steroid hormone biosynthesis, Chemical carcinogenesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism
|