| Gene Symbol |
PPM1H
|
| Entrez Gene |
57460
|
| Alt Symbol |
ARHCL1, NERPP-2C, URCC2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase, Mg2+/Mn2+ dependent, 1H
|
| Other Description |
neurite extension-related protein phosphatase related to PP2C|protein phosphatase 1H|protein phosphatase 1H (PP2C domain containing)|ras homolog gene family, member C like 1
|
| Swissprots |
B2RXG4 B1Q2A9 Q9ULR3 Q6PI86
|
| Accessions |
EAW97112 Q9ULR3 AB032983 BAA86471 AB084258 BAG16181 AK023315 BC040177 BC157843 AAI57844 BC160095 AAI60095 DA396561 XM_011538578 XP_011536880 XM_011538579 XP_011536881 NM_020700 NP_065751
|
| Function |
Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation. {ECO:0000269|PubMed:22586611}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:22586611}. Cytoplasm {ECO:0000269|PubMed:22586611}.
|
![Western Blot: PPM1H Overexpression Lysate (Adult Normal) [NBP2-06626] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PPM1H.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4719_PPM1H%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06626-img0001.jpg)