| Gene Symbol |
CD99
|
| Entrez Gene |
4267
|
| Alt Symbol |
HBA71, MIC2, MIC2X, MIC2Y, MSK5X
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD99 molecule
|
| Other Description |
CD99 antigen|E2 antigen|MIC2 (monoclonal antibody 12E7)|T-cell surface glycoprotein E2|antigen identified by monoclonal 12E7, Y homolog|antigen identified by monoclonal antibodies 12E7, F21 and O13|surface antigen MIC2
|
| Swissprots |
O00518 A6NIW1 P14209 Q6ICV7
|
| Accessions |
AAA59848 CBX53885 CDM22290 EAW98697 EAW98698 EAW98699 EAW98700 P14209 AK309517 AK313617 BAG36379 BC002584 AAH02584 BC003147 AAH03147 BC010109 AAH10109 BC021620 AAH21620 BC024310 AAH24310 CR450286 CAG29282 DQ891912 ABM82838 DT216927 M16279 AAA02999 U82164 AAB58501 X16996 CAA34863 XM_005274530 XP_005274587 XM_005274532 XP_005274589 XM_005274533 XP_005274590 XM_005274534 XP_005274591 XM_005274535 XP_005274592 XM_005274794 XP_005274851 XM_005274796 XP_005274853 XM_005274797 XP_005274854 XM_005274798 XP_005274855 XM_005274799 XP_005274856 NM_001122898 NP_001116370 NM_001277710 NP_001264639 NM_002414 NP_002405
|
| Function |
Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Top Pathways |
Leukocyte transendothelial migration, Cell adhesion molecules (CAMs)
|
![Western Blot: CD99 Overexpression Lysate (Adult Normal) [NBP2-04225] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CD99.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8053_CD99%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04225-img0001.jpg)