| Gene Symbol |
DAZ3
|
| Entrez Gene |
57054
|
| Alt Symbol |
pDP1679
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
deleted in azoospermia 3
|
| Other Description |
deleted in azoospermia protein 3
|
| Swissprots |
Q2KHN7 Q9NR90
|
| Accessions |
Q9NR90 AF248481 AAF91330 BC036648 BC113005 AAI13006 XM_011531505 XP_011529807 XM_011531506 XP_011529808 XM_011531507 XP_011529809 XM_011531508 XP_011529810 NM_020364 NP_065097
|
| Function |
RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11058556}. Nucleus {ECO:0000269|PubMed:11058556}. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
|
| Tissue Specificity |
Testis specific. {ECO:0000269|PubMed:10936047}.
|