Gene Symbol |
PTPN18
|
Entrez Gene |
26469
|
Alt Symbol |
BDP1, PTP-HSCF
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
|
Other Description |
brain-derived phosphatase|tyrosine-protein phosphatase non-receptor type 18
|
Swissprots |
B4E1E6 Q99952 Q53P42
|
Accessions |
AAY24077 EAW55617 EAW55618 EAW55619 EAW55620 EAW55621 Q99952 AK297884 BAG60207 AK303804 BAG64758 AK311140 BC024280 AAH24280 BC031076 BC041562 AAH41562 BC052800 AAH52800 BI261717 BM789073 CA310199 DN995571 X79568 CAA56105 XM_006712416 XP_006712479 XM_006712417 XP_006712480 NM_001142370 NP_001135842 NM_014369 NP_055184
|
Function |
Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
|
Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
|
Tissue Specificity |
Expressed in brain, colon and several tumor- derived cell lines. {ECO:0000269|PubMed:8950995}.
|