| Gene Symbol |
ARFGAP2
|
| Entrez Gene |
84364
|
| Alt Symbol |
IRZ, NBLA10535, ZFP289, ZNF289
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADP-ribosylation factor GTPase activating protein 2
|
| Other Description |
ADP-ribosylation factor GTPase-activating protein 2|GTPase-activating protein ZNF289|zinc finger protein 289, ID1 regulated
|
| Swissprots |
Q3LIF2 B7Z9M7 Q8N6H7 Q8N3I1 Q96SX7 D3DQQ9 B4DX29
|
| Accessions |
EAW67963 EAW67964 EAW67965 EAW67966 EAW67967 EAW67968 Q8N6H7 AB073358 BAE45716 AK027482 BAB55144 AK098324 BAG53612 AK129511 AK300347 BAH13265 AK301785 BAG63241 AK304541 BAG65339 AK315992 BAH14363 AL834337 CAD39004 BC030148 AAH30148 BC036823 BM827445 CD366084 EU832352 ACE87609 EU832437 ACE86922 XM_005253166 XP_005253223 XM_005253167 XP_005253224 XM_005253168 XP_005253225 XM_006718346 XP_006718409 XM_011520405 XP_011518707 NM_001242832 NP_001229761 NM_032389 NP_115765
|
| Function |
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. {ECO:0000269|PubMed:17760859}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17760859}. Golgi apparatus membrane {ECO:0000269|PubMed:17760859}; Peripheral membrane protein {ECO:0000269|PubMed:17760859}; Cytoplasmic side {ECO:0000269|PubMed:17760859}. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
|
| Top Pathways |
Endocytosis
|