| Gene Symbol |
Ugt3a2
|
| Entrez Gene |
223337
|
| Alt Symbol |
AI313915
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
UDP glycosyltransferases 3 family, polypeptide A2
|
| Other Description |
UDP glucuronosyltransferase 3 family, polypeptide A2|UDP-glucuronosyltransferase 3A2|UDPGT 3A2
|
| Swissprots |
A1A4B4 Q8JZZ0 Q8VC11 Q3UP49
|
| Accessions |
EDL03315 Q8JZZ0 AK041045 BAC30796 AK050128 BAC34080 AK052644 AK143815 BAE25548 BC022134 AAH22134 BC024453 AAH24453 BC034837 AAH34837 XM_006520049 XP_006520112 XM_011245349 XP_011243651 NM_144845 NP_659094
|
| Function |
UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in kidney, while it is expressed at low levels in liver. Not detected in other tissues examined. {ECO:0000269|PubMed:17050650}.
|