Gene Symbol |
PHKG1
|
Entrez Gene |
5260
|
Alt Symbol |
PHKG
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
phosphorylase kinase, gamma 1 (muscle)
|
Other Description |
PHK-gamma-M|phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform|phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform|phosphorylase kinase gamma|phosphorylase kinase subunit gamma-1|serine/threonine-protein kinase PHKG1
|
Swissprots |
Q75LP5 Q16816 B7Z1D0 F5H2S1
|
Accessions |
AAL36972 AAS07453 EAX07987 EAX07989 Q16816 AK293180 BAH11466 AK299429 BAH13029 AK300928 BAH13378 AK309503 AK312851 BAG35704 BC051327 AAH51327 BC069655 AAH69655 BC069679 AAH69679 BC069738 AAH69738 BC069754 AAH69754 BC074753 AAH74753 DB171823 X80590 CAA56681 XM_005271772 XP_005271829 NM_001258459 NP_001245388 NM_001258460 NP_001245389 NM_006213 NP_006204 NR_047689
|
Function |
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity). {ECO:0000250}.
|
Top Pathways |
Insulin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway
|