Gene Symbol | ADTRP |
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Entrez Gene | 84830 |
Alt Symbol | AIG1L, C6orf105, dJ413H6.1 |
Species | Human |
Gene Type | protein-coding |
Description | androgen-dependent TFPI-regulating protein |
Other Description | androgen-dependent TPF1-regulating protein |
Swissprots | B2R7T9 B4DV39 Q96IZ2 Q5THW1 |
Accessions | CCF76971 CCF76972 EAW55304 EAW55305 EAW55306 Q96IZ2 AI147084 AI336841 AJ420520 AK123258 AK300919 BAG62551 AK310611 AK313114 BAG35936 BC007011 AAH07011 BP330027 DC388625 XM_005249454 XP_005249511 XM_005249455 XP_005249512 XM_011514956 XP_011513258 XM_011514958 XP_011513260 XM_011514959 XP_011513261 XR_926322 NM_001143948 NP_001137420 NM_032744 NP_116133 |
Function | Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro). {ECO:0000269|PubMed:21868574}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21868574}; Multi-pass membrane protein {ECO:0000269|PubMed:21868574}. Note=Colocalized with TFPI and CAV1 in lipid rafts. |
Tissue Specificity | Expressed in cultured endothelial cells and in placenta. {ECO:0000269|PubMed:21868574}. |
C6orf105 CRISPR/Cas9 KO Plasmid (h) - sc-413707 from Santa Cruz Biotechnology
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C6orf105 HDR Plasmid (h) - sc-413707-HDR from Santa Cruz Biotechnology
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C6orf105 Double Nickase Plasmid (h) - sc-413707-NIC from Santa Cruz Biotechnology
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C6orf105 Double Nickase Plasmid (h2) - sc-413707-NIC-2 from Santa Cruz Biotechnology
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C6orf105 CRISPR Activation Plasmid (h) - sc-413707-ACT from Santa Cruz Biotechnology
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C6orf105 CRISPR Activation Plasmid (h2) - sc-413707-ACT-2 from Santa Cruz Biotechnology
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C6orf105 Lentiviral Activation Particles (h) - sc-413707-LAC from Santa Cruz Biotechnology
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C6orf105 Lentiviral Activation Particles (h2) - sc-413707-LAC-2 from Santa Cruz Biotechnology
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C6orf105 siRNA (h) - sc-95244 from Santa Cruz Biotechnology
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C6orf105 shRNA Plasmid (h) - sc-95244-SH from Santa Cruz Biotechnology
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C6orf105 shRNA (h) Lentiviral Particles - sc-95244-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN5009 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5009 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06728 from Sigma-Aldrich
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ADTRP siRNA (Human) - CRJ3636 from Cohesion Biosciences
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ADTRP - MBS8229159 from MyBioSource
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shRNA set against Human C6orf105 (NM_032744.3) - SHH252157 from Creative biogene
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Human ADTRP siRNA - orb274137 from Biorbyt
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ADTRP shRNA Plasmid (Human) - CHJ3636 from Cohesion Biosciences
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ADTRP miRNA 3'UTR clone - MiUTR4H-TG01112 from Creative biogene
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