Gene Symbol | PRDX4 |
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Entrez Gene | 10549 |
Alt Symbol | AOE37-2, AOE372, HEL-S-97n, PRX-4 |
Species | Human |
Gene Type | protein-coding |
Description | peroxiredoxin 4 |
Other Description | antioxidant enzyme AOE372|epididymis secretory sperm binding protein Li 97n|peroxiredoxin IV|peroxiredoxin-4|prx-IV|thioredoxin peroxidase (antioxidant enzyme)|thioredoxin peroxidase AO372|thioredoxin-dependent peroxide reductase A0372 |
Swissprots | Q6FHT3 Q13162 |
Accessions | EAW98996 Q13162 BC003609 AAH03609 BC007107 AAH07107 BC016770 AAH16770 CR541668 CAG46469 CR541705 CAG46506 DQ893599 ABM84525 DQ895027 ABM85953 FJ224297 ACI45989 U25182 AAB95175 XM_005274438 XP_005274495 NM_006406 NP_006397 |
Function | Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. {ECO:0000269|PubMed:9388242}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9388242}. Secreted {ECO:0000269|PubMed:9388242}. |
PRX IV CRISPR/Cas9 KO Plasmid (h) - sc-402821 from Santa Cruz Biotechnology
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PRX IV HDR Plasmid (h) - sc-402821-HDR from Santa Cruz Biotechnology
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PRX IV Double Nickase Plasmid (h) - sc-402821-NIC from Santa Cruz Biotechnology
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PRX IV Double Nickase Plasmid (h2) - sc-402821-NIC-2 from Santa Cruz Biotechnology
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PRX IV CRISPR Activation Plasmid (h) - sc-402821-ACT from Santa Cruz Biotechnology
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PRX IV CRISPR Activation Plasmid (h2) - sc-402821-ACT-2 from Santa Cruz Biotechnology
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PRX IV Lentiviral Activation Particles (h) - sc-402821-LAC from Santa Cruz Biotechnology
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PRX IV Lentiviral Activation Particles (h2) - sc-402821-LAC-2 from Santa Cruz Biotechnology
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PRX IV siRNA (h) - sc-40835 from Santa Cruz Biotechnology
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PRX IV shRNA Plasmid (h) - sc-40835-SH from Santa Cruz Biotechnology
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PRX IV shRNA (h) Lentiviral Particles - sc-40835-V from Santa Cruz Biotechnology
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Peroxiredoxin 4 RNAi - H00010549-R01 from Novus Biologicals
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MISSION® esiRNA - EHU040811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17385 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17385 from Sigma-Aldrich
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PRDX4 siRNA (Human) - CRH7170 from Cohesion Biosciences
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shRNA set against Human PRDX4 (NM_006406.1) - SHH382336 from Creative biogene
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shRNA set against Human PRDX4(NM_006406.1) - SHR138162 from Creative biogene
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Human PRDX4 siRNA - orb267672 from Biorbyt
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PRDX4 shRNA Plasmid (Human) - CHH7170 from Cohesion Biosciences
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PRDX4 miRNA 3'UTR clone - MiUTR1H-08237 from Creative biogene
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