Gene Symbol | ZNF24 |
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Entrez Gene | 7572 |
Alt Symbol | KOX17, RSG-A, ZNF191, ZSCAN3, Zfp191 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 24 |
Other Description | retinoic acid suppression protein A|zinc finger and SCAN domain-containing protein 3|zinc finger protein 191|zinc finger protein 24 (KOX 17)|zinc finger protein KOX17 |
Swissprots | Q6ICR5 P17028 O14754 Q53YE4 Q8IZN4 |
Accessions | AAB70216 EAX01348 EAX01349 EAX01350 P17028 AF038964 AAD19827 AF542097 AAN40767 AK021966 AK291246 BAF83935 BC003566 AAH03566 BC016801 AAH16801 BG436261 BT006658 AAP35304 CA314100 CR450328 CAG29324 HQ257967 ADR82721 HY101315 U68536 AAB37275 X52348 CAA36574 XM_005258341 XP_005258398 XM_005258342 XP_005258399 NM_001308123 NP_001295052 NM_006965 NP_008896 |
Function | Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro. {ECO:0000250, ECO:0000269|PubMed:10585455}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00187, ECO:0000269|PubMed:24224020}. |
Tissue Specificity | Expressed in many tissues except in heart. |
ZNF191 CRISPR/Cas9 KO Plasmid (h) - sc-408629 from Santa Cruz Biotechnology
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ZNF191 HDR Plasmid (h) - sc-408629-HDR from Santa Cruz Biotechnology
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ZNF191 Double Nickase Plasmid (h) - sc-408629-NIC from Santa Cruz Biotechnology
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ZNF191 Double Nickase Plasmid (h2) - sc-408629-NIC-2 from Santa Cruz Biotechnology
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ZNF191 CRISPR Activation Plasmid (h) - sc-408629-ACT from Santa Cruz Biotechnology
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ZNF191 CRISPR Activation Plasmid (h2) - sc-408629-ACT-2 from Santa Cruz Biotechnology
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ZNF191 Lentiviral Activation Particles (h) - sc-408629-LAC from Santa Cruz Biotechnology
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ZNF191 Lentiviral Activation Particles (h2) - sc-408629-LAC-2 from Santa Cruz Biotechnology
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ZNF191 siRNA (h) - sc-76969 from Santa Cruz Biotechnology
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ZNF191 shRNA Plasmid (h) - sc-76969-SH from Santa Cruz Biotechnology
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ZNF191 shRNA (h) Lentiviral Particles - sc-76969-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23333 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23333 from Sigma-Aldrich
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ZNF24 siRNA (Human) - CRH5177 from Cohesion Biosciences
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ZNF24 RNAi - H00007572-R01 from Novus Biologicals
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ZNF24 - MBS828273 from MyBioSource
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shRNA set against Human ZNF24 (NM_006965.2) - SHH453396 from Creative biogene
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Human ZNF24 siRNA - orb265679 from Biorbyt
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ZNF24 shRNA Plasmid (Human) - CHH5177 from Cohesion Biosciences
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