Gene Symbol | RAB5B |
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Entrez Gene | 5869 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAB5B, member RAS oncogene family |
Other Description | ras-related protein Rab-5B |
Swissprots | Q8IXL2 P35239 A8K982 Q6PIK9 P61020 P35277 B4DKD7 Q86TH0 |
Accessions | EAW96862 EAW96863 EAW96864 P61020 AF267863 AAG44732 AF498937 AAM21085 AK292597 BAF85286 AK296517 BAG59149 AK307468 AM393529 CAL38406 BC032740 AAH32740 BC040143 AAH40143 BC050558 AAH50558 BC056422 AAH56422 BC065298 AAH65298 BX537408 CAD97650 BX647808 CR536482 CAG38721 CR541690 CAG46491 DA401343 DA811144 X54871 CAA38653 XM_005269051 XP_005269108 XM_005269052 XP_005269109 NM_001252036 NP_001238965 NM_001252037 NP_001238966 NM_002868 NP_002859 |
Function | Protein transport. Probably involved in vesicular traffic (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:17081065}; Lipid-anchor {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Early endosome membrane {ECO:0000269|PubMed:17081065}; Lipid-anchor {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Enriched in stage I melanosomes. |
Top Pathways | Endocytosis, Vasopressin-regulated water reabsorption, Phagosome, Amoebiasis, Tuberculosis |
Rab 5B CRISPR/Cas9 KO Plasmid (h) - sc-401110 from Santa Cruz Biotechnology
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Rab 5B HDR Plasmid (h) - sc-401110-HDR from Santa Cruz Biotechnology
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Rab 5B Double Nickase Plasmid (h) - sc-401110-NIC from Santa Cruz Biotechnology
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Rab 5B Double Nickase Plasmid (h2) - sc-401110-NIC-2 from Santa Cruz Biotechnology
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Rab 5B CRISPR Activation Plasmid (h) - sc-401110-ACT from Santa Cruz Biotechnology
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Rab 5B CRISPR Activation Plasmid (h2) - sc-401110-ACT-2 from Santa Cruz Biotechnology
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Rab 5B Lentiviral Activation Particles (h) - sc-401110-LAC from Santa Cruz Biotechnology
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Rab 5B Lentiviral Activation Particles (h2) - sc-401110-LAC-2 from Santa Cruz Biotechnology
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Rab 5B siRNA (h) - sc-36346 from Santa Cruz Biotechnology
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Rab 5B shRNA Plasmid (h) - sc-36346-SH from Santa Cruz Biotechnology
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Rab 5B shRNA (h) Lentiviral Particles - sc-36346-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU085601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17860 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17860 from Sigma-Aldrich
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RAB5B siRNA (Human) - CRH3959 from Cohesion Biosciences
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RAB5B - MBS8221729 from MyBioSource
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shRNA set against Human RAB5B (NM_002868.3) - SHH388500 from Creative biogene
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Human RAB5B siRNA - orb264461 from Biorbyt
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RAB5B shRNA Plasmid (Human) - CHH3959 from Cohesion Biosciences
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