Gene Symbol | AKAP3 |
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Entrez Gene | 10566 |
Alt Symbol | AKAP 110, AKAP110, CT82, FSP95, HEL159, PRKA3, SOB1 |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 3 |
Other Description | A-kinase anchor protein 3|A-kinase anchor protein, 110kDa|Fibrous Sheath Protein of 95 kDa|cancer/testis antigen 82|epididymis luminal protein 159|fibrousheathin I|fibrousheathin-1|protein kinase A binding protein AKAP 110|protein kinase A-anchoring protein 3|sperm oocyte-binding protein 1 |
Swissprots | Q9UM61 O75945 Q86X01 O75969 |
Accessions | EAW88840 O75969 AF087003 AAC35854 AF093408 AAC63371 AI004486 AK074722 BAG51992 AK292451 BAF85140 BC047535 AAH47535 DB083340 EU794681 ACJ13735 U85715 AAD21218 XM_005253664 XP_005253721 XM_011520908 XP_011519210 XM_011520909 XP_011519211 XM_011520910 XP_011519212 NM_001278309 NP_001265238 NM_006422 NP_006413 |
Function | May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment. |
Tissue Specificity | Testis specific; only expressed in spermatids. |
AKAP 3 CRISPR/Cas9 KO Plasmid (h) - sc-408185 from Santa Cruz Biotechnology
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AKAP 3 HDR Plasmid (h) - sc-408185-HDR from Santa Cruz Biotechnology
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AKAP 3 Double Nickase Plasmid (h) - sc-408185-NIC from Santa Cruz Biotechnology
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AKAP 3 Double Nickase Plasmid (h2) - sc-408185-NIC-2 from Santa Cruz Biotechnology
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AKAP 3 CRISPR Activation Plasmid (h) - sc-408185-ACT from Santa Cruz Biotechnology
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AKAP 3 CRISPR Activation Plasmid (h2) - sc-408185-ACT-2 from Santa Cruz Biotechnology
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AKAP 3 Lentiviral Activation Particles (h) - sc-408185-LAC from Santa Cruz Biotechnology
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AKAP 3 Lentiviral Activation Particles (h2) - sc-408185-LAC-2 from Santa Cruz Biotechnology
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AKAP 3 siRNA (h) - sc-60143 from Santa Cruz Biotechnology
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AKAP 3 shRNA Plasmid (h) - sc-60143-SH from Santa Cruz Biotechnology
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AKAP 3 shRNA (h) Lentiviral Particles - sc-60143-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU042551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3009 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3009 from Sigma-Aldrich
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AKAP3 siRNA (Human) - CRH7187 from Cohesion Biosciences
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AKAP3 - MBS8223392 from MyBioSource
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shRNA set against Human Akap3 (NM_006422.2) - SHH234262 from Creative biogene
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shRNA set against Human AKAP3(NM_006422.2) - SHG050221 from Creative biogene
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Human AKAP3 siRNA - orb267689 from Biorbyt
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AKAP3 shRNA Plasmid (Human) - CHH7187 from Cohesion Biosciences
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AKAP3 miRNA 3'UTR clone - MiUTR1H-00268 from Creative biogene
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